Abstract
The use of metal-on-metal (MoM) bearings in total hip arthroplasty (THA) was popularized due to its enhanced wear profile and the ability to use large femoral heads to reduce post-operative instability. However, enthusiasm for the bearing declined following serious complications encountered at the primary articulation. This review discusses the development of MoM and the subsequent unexpected downstream challenges, most notably elevated serum metal ion levels, aseptic lymphocyte-dominated vasculitis-associated lesions (ALVAL), pseudotumor formation, and subsequent soft tissue and bone destruction. Both patient centered risk factors as well as component design led to high early failure rates resulting in product recalls and an overall decline in the use of MoM. In 2016, there is not a role for large-head MoM bearing in THA. Alternatively, the bearing has shown promise in hip resurfacing procedures for carefully selected patients.
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Hannouche D, Nich C, Bizot P, Meunier A, Nizard R, Sedel L. Fractures of ceramic bearings: history and present status. Clinical Orthopaedics and Related Research. 2003;417:19–26.
Traina F, De Fine M, Di Mrtino A, Faldini C. Fracture of ceramic bearing surfaces following total hip replacement: a systematic review. BioMed Res Int. 2013;1–8.
Senturk U, Perka C. Ceramic-on-ceramic bearings in total hip arthroplasty (THA). Z Orthop Unfall. 2015;153:198–202.
Baek SH, Kim WK, Kin JY, Kim SY. Do alumina matrix composite bearings decrease hip noises and bearing fractures at a minimum of 5 years after THA? Clinical Orthopaedic and Related Research. 2015; online 7/1/2015.
Jarrett CA, Ranawat AS, Bruzzone M, Blum YC, Rodriguez JA, Ranawat CS. The squeaking hip: a phenomenon of ceramic-on-ceramic total hip arthroplasty. J Bone Joint Surg Am. 2009;91(6):1344–9.
Williams D, Royle M, Norton M. Metal-on-metal hip resurfacing. The effect of cup position and component size on range of motion to impingement. The Journal of Arthroplasty. 2009;24:144–51.
Bedigrew KM, Ruh EL, Zhang Q, Clohisy JC, Barrach RL, Nunley RM. When to release patients to high impact activities after hip resurfacing. Clin Orthop Relat Res. 2012;470:299–306.
Doorn PF, Campbell PA, Worrall J, Benya PD, McKellop HA, Amstutz HC. Metal wear particle characterization from metal on metal total hip replacements: transmission electron microscopy study of periprosthetic tissues and isolated particles. Journal of Biomedical Materials Research. 1998;42:103–11.
Topolovec M, Cor A, Milosev I. Metal-on-metal vs. metal-on-polyethylene total hip arthroplasty tribological evaluation of retrieved components and periprosthetic tissue. Journal of the Mechanical Behavior of Biomedical Materials. 2014;34:243–52.
Willert HG, Buchhorn GH, Fayyazi A, Flury R, Windler M, Koster G, et al. Metal-on-metal bearings and hypersensitivity in patients with artificial hip joints. A clinical and histomorphological study. J Bone Joint Surg Am. 2005;87:28–36.
Bosker BH, Ettema HB, Van Rossum M, Boomsma MF, Kollen BJ, Maas M, et al. Pseudotumor formation and serum ions after large head metal-on-metal stemmed total hip replacement. Risk factors, time course and revisions in 706 hips. Arch Orthop Trauma Surg. 2015;135:417–25.
Engh CA, MacDonald SJ, Sritulanondha S, Korczak A, Naudie D, Engh C. Metal ion levels after metal-on-metal total hip arthroplasty. The Journal of Bone and Joint Surgery. 2014;96:448–55. Recent prospective study documenting increased metal ion levels in patients with metal-on-metal THA.
Bayley N, Kahn H, Grosso P, Hupel T, Stevens D, Snider M, et al. What are the predictors and prevalence of pseudotumor and elevated metal ions after large-diameter metal-on-metal THA? Clinical Orthopaedics and Related Research. 2015;473:477–84.
De Haan R, Pattyn C, Gill HS, Murray DW, Campbell PA, De Smet K. Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement. The Journal of Bone and Joint Surgery (Br). 2008;90-B:1291–7.
De Haan R, Campbell PA, Su EP, De Smet KA. Revision of metal-on-metal resurfacing arthroplasty of the hip. The influence of malpositioning of the components. The Journal of Bone and Joint Surgery (Br). 2008;90-B:1158–63.
Klein J. Molecular mechanisms of synovial joint lubrication. Proc Inst Mech. 2006;220:691–710.
Maskiewicz et al. Characterization of protein degradation in serum-based lubricants during simulation wear testing of metal-on-metal hip prostheses. J Biomed Mat. 2000;94:429–40.
Myant C, Cann P. On the matter of synovial fluid lubrication: implications for metal on metal hip tribology. J Mech Behav Biomed Mat. 2014;34:338–48.
Marker M, Grubl A, Riedl O, Heinze G, Pohanka E, Kotz R. Metal-on-metal hip implants: do they impair renal function in the long term? A 10-year follow-up study. Arch Orthop Trauma Surg. 2008;128:915–9.
Morin Y, Daniel P. Quebec beer-drinkers cardiomyopathy: etiological considerations. J Can Med Assoc. 1967;97:926.
Zywiel MG, Brandt JM, Overgaard CB, Cheung AC, Turgeon TR, Syed KA. Fatal cardiomyopathy after revision total hip replacement for fracture of a ceramic liner. The Bone and Joint Journal. 2013;95-B:31–7.
Ikeda T, Takahashi K, Kabata T, Sakagoshi D, Tomita K, Yamada M. Polyneuropathy caused by cobalt-chromium metallosis after total hip replacement. Muscle & Nerve. 2010;42:140–3.
Pelclova D, Sklensky M, Janicek P, Lach K. Severe cobalt intoxication following hip replacement revision: clinical features and outcome. Clinical Toxicology. 2012;50:262–5.
Raghunathan VK, Devey M, Hawkins S, Hails L, Davis SA, Mann S, et al. Influence of particle size and reactive oxygen species on cobalt chrome nanoparticle-mediated genotoxicity. Biomaterials. 2013;34:3559–70. Metal ions linked to genotoxicity.
Makela KT, Visuri T, Pulkkinen P, Eskelinen A, Remes V, Virolainen P, et al. Cancer incidence and cause-specific mortality in patients with metal-on-metal hip replacements in Finland. A population-based study with a mean follow-up of 4.6 (1–11) years. Acta Orthopaedica. 2014;85:32–8.
De Steiger RN, Hang JR, Miller LN, Graves SE, Davidson DC. Five-year results of the ASR XL acetabular system and the ASR Hip resurfacing system: an analysis from the Australian Orthopaedic Association National Joint Replacement Registry. Journal of Bone and Joint Surgery. 2011;93:2287–93.
Bernthal NM, Celestre PC, Stavrakis AI, Ludington JC, Oakes DA. Disappointing short-term results with the Depuy ASR XL metal-on metal total hip arthroplasty. The Journal of Arthroplasty. 2012;27:539–44.
Lehil MS, Bozic KJ. Trends in total hip arthroplasty implant utilization in the United States. The Journal of Arthroplasty. 2014;29:1915–8.
Lavernia CJ, Iacobelli DA, Villa JM, Jones K, Gonzalez JL, Jones WK. Trunion-head stresses in THA: are big heads trouble? The Journal of Arthroplasty. 2015;30:1085–8.
Kiran M, Boscainos PJ. Adverse reaction to metal debris in metal-on-polyethylene total hip arthroplasty using a titanium-molybdenum-zirconium-iron allow stem. The Journal of Arthroplasty. 2015;30:277–81.
Langton DJ, Jameson SS, Joyce TJ, Gandhi JN, Sidaginamale R, Mereddy P, et al. Accelerating failure rate of the ASR total hip replacement. The Journal of Bone and Joint Surgery. 2011;93B:1011–6.
Johnson AJ, Zywiel MG, Hooper H, Mont MA. Narrowed indications improve outcomes for hip resurfacing arthroplasty. Bulletin of the NYU Hospital for Joint Diseases. 2011;69:27–9.
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Edward J. Silverman, Blair Ashley, and Neil P. Sheth declare that they have no conflict of interest.
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Silverman, E.J., Ashley, B. & Sheth, N.P. Metal-on-metal total hip arthroplasty: is there still a role in 2016?. Curr Rev Musculoskelet Med 9, 93–96 (2016). https://doi.org/10.1007/s12178-016-9323-1
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DOI: https://doi.org/10.1007/s12178-016-9323-1