In this paper, a novel trehalose sensor based on micro/nano-Ni foam modified with graphene oxidated (GO) and a non-linear data analysis model was proposed. A three-electrode electrochemical detection system, GO-modified Ni foam material as the working electrode, Ag/AgCl (saturated KCl) electrode as the reference electrode, and Pt electrode as the counter electrode, was utilized as a detecting system. Trehalose with different concentrations was measured by cyclic voltammetry (CV) and amperometric i-t curve (i-t) methods. Results showed that the sensitivity of the proposed sensor was 1.66 ± 0.07 mA cm−2 Mm−1, and the detecting limit was 37.1 μM (S/N = 3). The sensitivity of the unmodified Ni foam electrode was 0.23 ± 0.01 mA cm−2 mM−1, and the detecting limit was 52.3 μM (S/N = 3). Results demonstrated that GO-modified Ni foam electrode presented higher sensitivity and lower detecting limit than unmodified Ni foam electrode. Control experiments indicated that they presented specific responses to trehalose. It has some advantages including quick response, high sensitivity, and low detection limit.
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This work is financially supported by the Scientific Research Project of National Natural Science Foundation of China (No. U1709212), Scientific Research Project of Zhejiang Province (Grant No. 2019C02075, LGG18F030012, LGG19F010012), Natural Science Foundation of Zhejiang Province (Grant No. LY19F030023), and College Student Research Program of Zhejiang Province and Zhejiang A&F University.
All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.
Informed consent not applicable.
Conflict of Interest
Guohua Hui has received a research grant from the Scientific Research Project of Zhejiang Province (Grant No. 2019C02075) and the Scientific Research Project of the National Natural Science Foundation of China (No. U1709212). Yuanyuan Gao has received a research grant from the Natural Science Foundation of Zhejiang Province (Grant No. LY19F030023). Xiaomei Yi has received a research grant from the Scientific Research Project of Zhejiang Province (Grant No. LGG19F010012). Xudong Fang declares that he has no conflict of interest. Zhenghao Mei declares that he has no conflict of interest. Jiaqi Chen declares that she has no conflict of interest. Siyi Xiong declares that she has no conflict of interest. Jingyuan Ning declares that he has no conflict of interest. Chenhao Jiang declares that he has no conflict of interest. Yuanyuan Gao declares that she has no conflict of interest. Xiaomei Yi declares that she has no conflict of interest. Guohua Hui declares that he has no conflict of interest.
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Fang, X., Mei, Z., Chen, J. et al. A Trehalose Quantitative Sensor Based on Ni Foam Material Modified with Graphene Oxidated and Non-linear Analysis Model. Food Anal. Methods 14, 1977–1985 (2021). https://doi.org/10.1007/s12161-021-02028-x