Food Analytical Methods

, Volume 11, Issue 5, pp 1476–1484 | Cite as

Simultaneous Solid-Phase Extraction and Determination of Three Bisphenols in Water Samples and Orange Juice by a Porous β-Cyclodextrin Polymer

  • Yarong Li
  • Pengpeng Lu
  • Jincheng Cheng
  • Qiang Wang
  • Chiyang He


A porous β-cyclodextrin polymer (P-CDP) was used as a new sorbent for simultaneous solid-phase extraction (SPE) and determination of bisphenol A (BPA), bisphenol F (BPF), and bisphenol AF (BPAF). The P-CDP was obtained via the cross-linking of β-cyclodextrin with tetrafluoroterephthalonitrile, and then was characterized by FT-IR spectroscopy, scanning electron microscopy, nitrogen adsorption-desorption isotherms, and thermo-gravimetric analysis. Adsorption tests showed that the P-CDP had good binding ability and fast uptake kinetics for three bisphenols. When used as a SPE sorbent for three bisphenols, P-CDP showed high extraction efficiencies, high enrichment factors, and good reusability. Based on the P-CDP sorbent, a new SPE-HPLC-UV method was developed and successfully applied to the detection of three bisphenols in real samples. The recoveries of BPF, BPA, and BPAF in water samples were 91.2–102.6% (RSD = 1.4–2.9%), 98.0–101.2% (RSD = 1.3–2.7%), and 96.3%–103.7% (RSD = 1.3–2.9%), respectively. Moreover, the recoveries of BPF, BPA, and BPAF in orange juice were 94.3–97.1% (RSD = 1.4–2.9%), 102.7–103.6% (RSD = 1.7–3.5%), and 94.5–101.0% (RSD = 1.3–2.8%), respectively. The limits of detection (S/N = 3) and the limits of quantification (S/N = 10) for all analytes were 0.3 and 1.0 ng/mL, respectively. Therefore, P-CDP can be used as a good SPE sorbent for the simultaneous determination of BPA, BPF, and BPAF in environmental water samples and beverages.


Porous β-cyclodextrin polymer Solid-phase extraction Bisphenols Water samples Beverage High-performance liquid chromatography 



This work was supported by the National Nature Science Foundation of China (21277106) and the Science and Technology Program of Wuhan (2015060101010034).


Dr. Qiang Wang has received research grant from the National Natural Science Foundation of China. Dr. Chiyang He has research grant from the Science and Technology Program of Wuhan.

Compliance with Ethical Standards

Conflict of Interest

Yarong Li declares that she has no conflict of interest. Pengpeng Lu declares that he has no conflict of interest. Jincheng Cheng declares that she has no conflict of interest. Qiang Wang declares that he has no conflict of interest. Chiyang He declares that he has no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants performed by any of the authors.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


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© Springer Science+Business Media, LLC, part of Springer Nature 2017

Authors and Affiliations

  1. 1.School of Chemistry and Chemical EngineeringWuhan Textile UniversityWuhanChina

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