Advertisement

Food Analytical Methods

, Volume 10, Issue 7, pp 2412–2421 | Cite as

New Perspectives of Quantum Dots in the Food Field: Determination of β-Carotene in Tropical Fruit Juices and Food Supplements

  • J. Jiménez-López
  • J.L.M. Santos
  • P. Ortega-Barrales
  • A. Ruiz-Medina
Article
  • 155 Downloads

Abstract

A novel and simple method for the determination of β-carotene, a carotenoid abundant in plants and fruits, is proposed. Multicommutated flow injection analysis (MCFIA) has been applied as automated flow methodology to the analysis of β-carotene in tropical fruit juices and food supplements, making use of the quenching effect caused by this analyte over glutathione-capped CdTe quantum dots (QDs) fluorescence signal. Under optimized conditions, the method was linear in the range of 0.3–15 μg mL−1, with a detection limit of 0.09 μg mL−1 and relative standard deviations lower than 3%. The determination rate was of about 80 h−1, and results were in good agreement with those provided by both the manufacturer and a chromatographic reference method.

Keywords

β-Carotene Luminescence Glutathione-capped CdTe quantum dots Fruit juices Food supplements 

Notes

Acknowledgements

J.J.L. acknowledges research scholarship from Spanish Government (“Ministerio de Educación y Ciencia”).

Compliance with Ethical Standards

Funding

This study was funded by the “Ministerio de Economía y Competitividad” (grant number CTQ2016-7511-R).

Conflict of Interest

J. Jiménez-López declares that she has no conflict of interest. J.L.M. Santos declares that he has no conflict of interest. P. Ortega-Barrales declares that she has no conflict of interest. A. Ruiz-Medina declares that he has no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed Consent

Not applicable.

References

  1. Andrés V, Villanueva MJ, Tenorio MD (2014) Simultaneous determination of tocopherols, retinol, ester derivatives and β-carotene in milk- and soy-juice based beverages by HPLC with diode-array detection. LWT - Food Sci Technol 58:557–562CrossRefGoogle Scholar
  2. Brabcová I, Hlaváčková M, Šatínský D, Solich P (2013) A rapid HPLC column switching method for sample preparation and determination of β-carotene in food supplements. Food Chem 141:1433–1437CrossRefGoogle Scholar
  3. Costa-Fernandez JM, Pereiro R, Sanz-Medel A (2006) The use of luminescent quantum dots for optical sensing. Trac-Trend Anal Chem 25:207–218CrossRefGoogle Scholar
  4. Chiosa V, Mandravel C, Kleinjans JCS, Moonen E (2005) Determination of b-carotene concentration in orange and apple juice and in vitamin supplemented drinks. An Univ Bucuresti : Chimie 1-2:253–258Google Scholar
  5. De Nardo T, Shiroma-Kian C, Halim Y, Francis D, Rodriguez-Saona LE (2009) Rapid and simultaneous determination of lycopene and β-carotene contents in tomato juice by infrared spectroscopy. J Agr Food Chem 57:1105–1112CrossRefGoogle Scholar
  6. Frigerio C, Ribeiro DSM, Rodrigues SSM, Abreu VLRG, Barbosa JAC, Prior JAV, Marques KL, Santos JLM (2012) Application of quantum dots as analytical tools in automated chemical analysis: a review. Anal Chim Acta 735:9–22CrossRefGoogle Scholar
  7. Garewal HS, Schantz S (1995) EMerging role of β-carotene and antioxidant nutrients in prevention of oral cancer. Arch Otolaryngol Head Neck Surg 121:141–144CrossRefGoogle Scholar
  8. Giuffrida D, Torre G, Dugo P, Dugo G (2013) Determination of the carotenoid profile in peach fruits, juice and jam. Fruits 68:39–44CrossRefGoogle Scholar
  9. Group TA-TBCCPS (1994) The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 330:1029–1035CrossRefGoogle Scholar
  10. Ji X, Palui G, Avellini T, Na HB, Yi C, Knappenberger KL, Mattoussi H (2012) On the pH-dependent quenching of quantum dot photoluminescence by redox active dopamine. J Am Chem Soc 134:6006–6017CrossRefGoogle Scholar
  11. Jimenez-López J, Molina-García L, Rodrigues SSM, Santos JLM, Ortega-Barrales P, Ruiz-Medina A (2016) Automated determination of rifamycins making use of MPA–CdTe quantum dots. J Lumin 175:158–164CrossRefGoogle Scholar
  12. Jiménez-López J, Ortega-Barrales P, Ruiz-Medina A (2016) Development of an semi-automatic and sensitive photochemically induced fluorescence sensor for the determination of thiamethoxam in vegetables. Talanta 149:149–155CrossRefGoogle Scholar
  13. Li Q, Tan X, Li J, Pan L, Liu X (2015) Glutathione-capped CdTe nanocrystals as probe for the determination of fenbendazole. Spectrochim Acta Part A Mol Biomol Spectrosc 141:10–15CrossRefGoogle Scholar
  14. Llorent-Martínez EJ, Molina-García L, Fernández-de Córdova ML, Santos JLM, Rodrigues SSM, Ruiz-Medina A (2013a) A novel multi-commutated method for the determination of hydroxytyrosol in enriched foods using mercaptopropionic acid-capped CdTe quantum dots. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 30:1485–1492CrossRefGoogle Scholar
  15. Llorent-Martínez EJ, Molina-García L, Kwiatkowski R, Ruiz-Medina A (2013b) Application of quantum dots in clinical and alimentary fields using multicommutated flow injection analysis. Talanta 109:203–208CrossRefGoogle Scholar
  16. Mayne ST (1996) Beta-carotene, carotenoids, and disease prevention in humans. FASEB J 10:690–701Google Scholar
  17. Melavanki RM, Kusanur RA, Kadadevaramath JS, Kulakarni MV (2009) Quenching mechanisms of 5BAMC by aniline in different solvents using Stern–Volmer plots. J Lumin 129:1298–1303CrossRefGoogle Scholar
  18. Molina-García L, Fernández-de Córdova ML, Ruiz-Medina A (2012) Analysis of bisphenol A in milk by using a multicommuted fluorimetric sensor. Talanta 96:195–201CrossRefGoogle Scholar
  19. Molina-García L, Llorent-Martínez EJ, Fernández-de Córdova ML, Santos JLM, Rodrigues SSM, Ruiz-Medina A (2013) Study of the quenching effect of quinolones over CdTe-quantum dots using sequential injection analysis and multicommutation. J Pharm Biomed Anal 80:147–154CrossRefGoogle Scholar
  20. Qian HF, Dong CQ, Weng JF, Ren JC (2006) Facile one-pot synthesis of luminescent, water-soluble, and biocompatible glutathione-coated CdTe nanocrystals. Small 2:747–751CrossRefGoogle Scholar
  21. Raymo FM, Yildiz I (2007) Luminescent chemosensors based on semiconductor quantum dots. Phys Chem Chem Phys 9:2036–2043CrossRefGoogle Scholar
  22. Rodrigues SSM, Ribeiro DSM, Molina-Garcia L, Ruiz Medina A, Prior JAV, Santos JLM (2014) Fluorescence enhancement of CdTe MPA-capped quantum dots by glutathione for hydrogen peroxide determination. Talanta 122:157–165CrossRefGoogle Scholar
  23. Ruedas-Rama MJ, Walters JD, Orte A, Hall EAH (2012) Fluorescent nanoparticles for intracellular sensing: a review. Anal Chim Acta 751:1–23CrossRefGoogle Scholar
  24. Rungpichayapichet P, Mahayothee B, Khuwijitjaru P, Nagle M, Müller J (2015) Non-destructive determination of β-carotene content in mango by near-infrared spectroscopy compared with colorimetric measurements. J Food Compos Anal 38:32–41CrossRefGoogle Scholar
  25. Xiangzhao A, Qiang M, Xingguang S (2013) Nanosensor for dopamine and glutathione based on the quenching and recovery of the fluorescence of silica-coated quantum dots. Microchim Acta 180:269–277CrossRefGoogle Scholar
  26. Yang Q, Tan X, Yang J (2015) Sensitive determination of enoxacin in pharmaceutical formulations by its quench effect on the fluorescence of glutathione-capped CdTe quantum dots. Luminescence 31:241–246CrossRefGoogle Scholar
  27. Yu WW, Qu LH, Guo WZ, Peng XG (2003) Experimental determination of the extinction coefficient of CdTe, CdSe, and CdS nanocrystals. Chem Mater 15:2854–2860CrossRefGoogle Scholar
  28. Yuan J, Guo W, Yin J, Wang E (2009) Glutathione-capped CdTe quantum dots for the sensitive detection of glucose. Talanta 77:1858–1863CrossRefGoogle Scholar
  29. Zou L, Gu Z, Zhang N, Zhang Y, Fang Z, Zhu W, Zhong X (2008) Ultrafast synthesis of highly luminescent green- to near infrared-emitting CdTe nanocrystals in aqueous phase. J Mater Chem 18:2807–2815CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • J. Jiménez-López
    • 1
  • J.L.M. Santos
    • 2
  • P. Ortega-Barrales
    • 1
  • A. Ruiz-Medina
    • 1
  1. 1.Department of Physical and Analytical Chemistry, Faculty of Experimental SciencesUniversity of Jaén, Campus de las LagunillasJaénSpain
  2. 2.REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of PharmacyPorto UniversityPortoPortugal

Personalised recommendations