Food Analytical Methods

, Volume 10, Issue 7, pp 2593–2606 | Cite as

A New Core@Shell Silica-Coated Magnetic Molecular Imprinted Nanoparticles for Selective Detection of Sunset Yellow in Food Samples

  • Majid Arvand
  • Zahra Erfanifar
  • Masoomeh Sayyar Ardaki


In this work, silica-coated magnetic nanoparticles were used as seed particles in the production of molecularly imprinted polymer (MIP) shells by copolymerization of ethylene glycol dimethacrylate with methacrylic acid in the presence of sunset yellow (SY) and an appropriate porogenic solvent. Thereafter, the MIP sensor was designed by covering a layer of core-shell MIP nanoparticles on a graphite-modified glassy carbon electrode (Gr/GCE). The results indicated that the MIP sensor could remarkably increase the peak current of SY and exhibited an excellent recognition capacity toward it compared with other structurally similar molecules. The detection limit of 5.5 nmol/L and two linear calibration ranges of 0.0085–1 and 1–30 μmol/L were obtained for SY determination. The proposed sensor was successfully applied for the determination of SY in several food samples without complex sample pretreatment.


Sunset yellow Food colorants Core-shell MIP nanoparticles Surface molecular imprinting technique MIP sensor Voltammetry 



The authors are thankful to the post-graduate office of Guilan University for the support of this work.

Compliance with Ethical Standards


This study was funded by Guilan University.

Conflict of Interest

M. Arvand declares that he has no conflict of interest. Z. Erfanifar declares that he has no conflict of interest. M. Sayyar Ardaki declares that he has no conflict of interest.

Ethical Approval

All procedures performed in studies were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

This article does not contain any studies with human or animal subjects performed by any of the authors.

Informed Consent

Not applicable.

Supplementary material

12161_2017_803_MOESM1_ESM.docx (2.4 mb)
ESM 1 (DOCX 2433 kb)


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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Majid Arvand
    • 1
  • Zahra Erfanifar
    • 1
  • Masoomeh Sayyar Ardaki
    • 1
  1. 1.Electroanalytical Chemistry Laboratory, Faculty of ScienceUniversity of GuilanRashtIran

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