Skip to main content
Log in

Do human menstrual-cycle pheromones exist?

  • Published:
Human Nature Aims and scope Submit manuscript

Abstract

Research over the past 15 years indicates, contrary to earlier results, that women do not synchronize their menstrual cycles. If women do not synchronize their cycles, this implies there is no mechanism for synchronizing cycles. Since a pheromone mechanism of synchronization is the only plausible mechanism that has been proposed, it follows that that there are no pheromones that modulate the length of menstrual cycles. To test this hypothesis, eight studies were reviewed that reported pheromone effects on menstrual cycles, other behavior, or physiological correlates in women. The prediction was that serious problems would be found in each of these studies. As predicted, serious problems were found in all eight studies. Taken together, these results cast doubt on the existence of pheromones that modulate the length of menstrual cycles.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Arden, M. A., and L. Dye 1998 The Assessment of Menstrual Synchrony: Comment on Weller and Weller (1997). Journal of Comparative Psychology 112:323–324.

    Article  Google Scholar 

  • French, J. A., and J. A. Stribley 1985 Synchronization of Ovarian Cycles within and between Social Groups in Golden Lion Tamarins (Leontopithecus rosalia). American Journal of Primatology 12:469–478.

    Article  Google Scholar 

  • Gattermann, R., K. Ulbrich, and R. Weinandy 2002 Asynchrony in the Estrous Cycles of Golden Hamsters (Mesocricetus auratus). Hormones and Behavior 242:70–77.

    Article  Google Scholar 

  • Handelmann, G., R. Ravizza, and W. J. Ray 1980 Social Dominance Determines Estrous Entrainment among Female Hamsters. Hormones and Behavior 14:107–115.

    Article  Google Scholar 

  • Harlow, S. D., X. Lin, and M. J. Ho 2000 Analysis of Menstrual Diary Data across the Reproductive Life Span: Applicability of the Bipartite Model Approach and the Importance of Within-Woman Variance. Journal of Clinical Epidemiology 53:722–733.

    Article  Google Scholar 

  • Jacob S., N. A. Spencer, S. B. Bullivant, S. A. Sellergren, J. A. Mennella, and M. K. McClintock 2004 Effects of Breastfeeding Chemosignals on the Human Menstrual Cycle. Human Reproduction 19:422–429.

    Article  Google Scholar 

  • Matsumoto-oda, A., and E. Kasuya 2005 Proximity and Estrous Synchrony in Mahale Chimpanzees. American Journal of Primatology 66:159–166.

    Article  Google Scholar 

  • McClintock, M. K. 1971 Menstrual Synchrony and Suppression. Nature 229:244–245.

    Article  Google Scholar 

  • McClintock, M. K. 1978 Estrous Synchrony and its Mediation by Airborne Chemical Communication (Rattus norvegicus). Hormones and Behavior 10:264–276.

    Article  Google Scholar 

  • McClintock, M. K. 1984 Estrous Synchrony: Modulation of Ovarian Cycle Length by Female Pheromones. Physiology and Behavior 32:701–705.

    Article  Google Scholar 

  • McCoy, N. L., and L. Pitino 2002 Pheromone Influences on Sociosexual Behavior in Young Women. Physiology and Behavior 75:367–375.

    Article  Google Scholar 

  • Monfort, S. L., M. Bush, and D. E. Wildt 1996 Natural and Induced Ovarian Synchrony in Golden Lion Tamarins (Leontopithecus rosalia). Biology of Reproduction 55:875–882.

    Article  Google Scholar 

  • Morofushi, M., K. Shinohara, T. Funabashi, and F. Kimura 2000 Positive Relationship between Menstrual Synchrony and Ability to Smell. Chemical Senses 25:407–411.

    Article  Google Scholar 

  • Popper, K. 1959 The Logic of Scientific Discovery. London: Hutchinson.

    Google Scholar 

  • Preti, G. 1987 Reply to Wilson. Hormones and Behavior 20:547–550.

    Article  Google Scholar 

  • Preti, G., W. B. Cutler, C. M. Christensen, H. Lawley, G. R. Huggins, and C. R. Garcia 1987 Human Axillary Extracts: Analysis of Compounds from Samples Which Influence Menstrual Timing. Journal Chemical Ecology 13:717–731.

    Article  Google Scholar 

  • Preti, G., W. B. Cutler, C. R. Garcia, A. Krieger, G. R. Huggins, and H. J. Lawley 1986 Human Axillary Secretions Influence Women’s Menstrual Cycles: The Role of Donor Extract of Females. Hormones and Behavior 20:474–482.

    Article  Google Scholar 

  • Russell, M. J., G. M. Switz, and K. Thompson 1980 Olfactory Influences on the Human Menstrual Cycle. Pharmacology Biochemistry & Behavior 13:737–738.

    Article  Google Scholar 

  • Schank, J. C. 1997 Problems with Dimensionless Measurement Models of Synchrony in Biological Systems. American Journal Primatololgy 41:65–85.

    Article  Google Scholar 

  • Schank, J. C. 2000a Menstrual-Cycle Variability and Measurement: Further Cause for Doubt. Psychoneuroendocrinology 25:837–847.

    Article  Google Scholar 

  • 2000b Can Pseudo Entrainment Explain the Synchrony of Estrous Cycles among Golden Hamsters (Mesocricetus auratus)? Hormones and Behavior 38:94–101.

    Article  Google Scholar 

  • 2001a Do Norway Rats (Rattus norvegicus) Synchronize Their Estrous Cycles? Physiology and Behavior 72:129–139.

    Article  Google Scholar 

  • 2001b Menstrual-Cycle Synchrony: Problems and New Directions for Research. Journal of Comparative Psychology 115:3–15.

    Article  Google Scholar 

  • 2001c Oestrous and Birth Synchrony in Norway Rats, Rattus norvegicus. Animal Behaviour 62:409–415.

    Article  Google Scholar 

  • 2001d Measurement and Cycle Variability: Reexamining the Case for Ovarian-Cycle Synchrony in Primates. Behavioural Processes 56:131–146.

    Article  Google Scholar 

  • 2004 Avoiding Synchrony as a Strategy of Female Mate Choice. Nonlinear Dynamics, Psychology, and Life Sciences 8:147–176.

    Google Scholar 

  • Schank, J. C., and M. K. McClintock 1992 A Coupled-Oscillator Model of Ovarian-Cycle Synchrony among Female Rats. Journal of Theoretical Biology 157:317–362.

    Article  Google Scholar 

  • 1997 Ovulatory Pheromone Shortens Ovarian Cycles of Female Rats Living in Olfactory Isolation. Physiology and Behavior 62:899–904.

    Article  Google Scholar 

  • Shinohara K., M. Morofushi, T. Funabashi, D. Mitsushima, and F. Kimura 2000 Effects of 5a-androst-16-en-3a-ol on the Pulsatile Secretion of Luteinizing Hormone in Human Females. Chemical Senses 25:465–267.

    Article  Google Scholar 

  • Shinohara K., M. Morofushi, T. Funabashi, and F. Kimura 2001 Axillary Pheromones Modulate Pulsatile LH Secretion in Humans. Neuroreport 12:893–895.

    Article  Google Scholar 

  • Stephens, M. A. 1965 The Goodness-of-fit Statistic VN: Distribution and Significance Points. Biometrika 52:309–321.

    Google Scholar 

  • Stern, K. N. 1992 Ovulation in Women: Methods of Detection, Behavioral Correlates, and Pheromone Regulation. Ph.D. Thesis, University of Chicago.

  • Stern, K., and M. K. McClintock 1998 Regulation of Ovulation by Human Pheromones. Nature 392:177–178.

    Article  Google Scholar 

  • Strassmann, B. L. 1997 The Biology of Menstruation in Homo sapiens: Total Lifetime Menses, Fecundity, and Nonsynchrony in a Natural Fertility Population. Current Anthropology 38:123–129.

    Article  Google Scholar 

  • 1999 Menstrual Synchrony Pheromones: Cause for Doubt. Human Reproduction 14:579–580.

    Article  Google Scholar 

  • Trevathan, W. R., M. H. Burleson, and W. L. Gregory 1993 No Evidence for Menstrual Synchrony in Lesbian Couples. Psychoneuroendocrinology 18:425–435.

    Article  Google Scholar 

  • Wallis, J. 1985 Synchrony of Estrous Swelling in Captive Group-Living Chimpanzees (Pan troglodytes). International Juornal of Primatology 6:335–350.

    Article  Google Scholar 

  • Wilson, H. C. 1987 Female Axillary Secretions Influence Women’s Menstrual Cycles: A Critique. Hormones and Behavior 21:536–550.

    Article  Google Scholar 

  • 1992 A Critical Review of Menstrual Synchrony Research. Psychoneuroendocrinology 17:565–591.

    Article  Google Scholar 

  • Wilson, H. C., S. H. Kiefhaber, and V. Gravel 1991 Two Studies of Menstrual Synchrony: Negative Results. Psychoneuroendocrinology 16:353–359.

    Article  Google Scholar 

  • Winfree, A. T. 1980 The Geometry of Biological Time. Berlin: Springer-Verlag.

    Google Scholar 

  • Yang, Z., and J. C. Schank 2006 Women Do Not Synchronize Their Menstrual Cycles. Human Nature 17:433–447.

    Google Scholar 

  • Ziomkeiwicz, Anna 2006 Menstrual Synchrony: Fact or Artifact? Human Nature 17:419–432.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jeffrey C. Schank.

Additional information

Jeff Schank is associate professor of psychology at the University of California, Davis. His main research interests are in computational and biorobotic modeling of group behavior and the development of sensorimotor behavior in animals.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schank, J.C. Do human menstrual-cycle pheromones exist?. Hum Nat 17, 448–470 (2006). https://doi.org/10.1007/s12110-006-1006-y

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12110-006-1006-y

Key words

Navigation