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Sine Qua Non: Sinonasal Inverted Papilloma

  • Sine qua non Radiology-Pathology
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Head and Neck Pathology Aims and scope Submit manuscript


Inverted papilloma (IP) is a common proliferation of squamous epithelial cells of the sinonasal tract. Although considered benign, IP is known to cause local destruction, has a high rate of recurrence, and a low, but significant rate of malignant transformation. Differentiating an IP from its histologic mimickers is essential for appropriate risk stratification and long-term surveillance. A classic case of sinonasal inverted papilloma is discussed.

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Correspondence to Frederic C. Jewett III.

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Frederic C. Jewett declares that he has no conflict of interest. Michael Coulter declares that he has no conflict of interest. Brenda L. Nelson declares that he has no conflict of interest.

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Jewett, F.C., Coulter, M.J. & Nelson, B.L. Sine Qua Non: Sinonasal Inverted Papilloma. Head and Neck Pathol 15, 950–954 (2021).

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