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Primary Leiomyosarcoma of the Buccal Mucosa: Report of a Case and Review of the Literature

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Abstract

This clinicopathologic study of primary oral leiomyosarcoma of the buccal mucosa involves a literature review of 15 cases with the addition of our report of a case. The demographic details, tumor size, treatment and outcome are documented for all the cases. In addition, this review examines the histologic features of leiomyosarcoma while noting that differentiation from other spindle cell tumors can be challenging, underscoring the necessity of an immunohistochemical work up for an accurate diagnosis. The unpredictability of the clinical behavior of these aggressive tumors requires, at the very least, wide local surgical excision and prolonged follow up.

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Authors and Affiliations

  1. School of Dentistry, University of Michigan, 1011 N University Ave, Ann Arbor, MI, 48109, USA

    Eugene M. Ko

  2. Department of Pathology, University of Michigan, Ann Arbor, MI, USA

    Jonathan B. McHugh

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  1. Eugene M. Ko
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  2. Jonathan B. McHugh
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Correspondence to Eugene M. Ko.

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Authors Eugene M. Ko and Jonathan McHugh declares that they have no conflict of interest.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Ko, E.M., McHugh, J.B. Primary Leiomyosarcoma of the Buccal Mucosa: Report of a Case and Review of the Literature. Head and Neck Pathol 12, 529–533 (2018). https://doi.org/10.1007/s12105-018-0907-5

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  • DOI: https://doi.org/10.1007/s12105-018-0907-5

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