Head and Neck Pathology

, Volume 6, Issue 4, pp 451–454 | Cite as

Epithelioid Osteoblastoma

  • Jennifer D. Britt
  • Mark D. Murphey
  • James T. CastleEmail author
Sine qua non Radiology-Pathology


A 19-year-old Asian male presented with facial pain of 2 1/2 months duration that was believed to be dental-related. Root canal therapy and multiple extractions failed to alleviate the patient’s discomfort. Subsequent CT images demonstrated an extensive mass in the left maxillary sinus.

Radiographic Features

Computed tomography of the paranasal sinuses using Landmarx protocol was performed using axial images without the administration of intravenous contrast material. Axial, sagittal and coronal reformatted images of the paranasal sinuses were obtained. CT images revealed opacification of the left maxillary sinus by a lesion with a calcific rim. There were additional areas of punctate calcifications within the lesion which represented matrix mineralization (Fig.  1). The lesion induced moderate expansile remodeling of the left maxillary sinus and mucosal thickening surrounding the lesion (Fig.  2). There were additional mucosal thickenings of the nasal cavity, ethmoid sinus, and...


Osteosarcoma Root Canal Osteoblastoma Left Maxillary Sinus Root Canal Therapy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Gnepp DR. Diagnostic surgical pathology of the head and neck. 2nd ed. Philadelphia: Saunders-Elsevier; 2009. p. 732–4.Google Scholar
  2. 2.
    Vigneswaran N, Fernandes R, Rodu B, et al. Aggressive osteoblastoma of the mandible closely simulating calcifying epithelial odontogenic tumor. Pathol Res Pract. 2001;197:569–76.PubMedGoogle Scholar
  3. 3.
    Dorfman H, Weiss S. Borderline osteoblastic tumors: problems in the differential diagnosis of aggressive osteoblastoma and low-grade osteosarcoma. Semin Diagn Pathol. 1984;1:215–34.PubMedGoogle Scholar
  4. 4.
    Harrington C, Accurso B, Kalmar JR, et al. Aggressive osteoblastoma of the maxilla: a case report and review of the literature. Head Neck Pathol. 2011;5:165–70.PubMedCrossRefGoogle Scholar
  5. 5.
    Lypka MA, Goos RR, Yamashita D-DR, Melrose R. Aggressive osteoblastoma of the mandible. Int J Oral Maxillofac Surg. 2008;37:675–8.PubMedCrossRefGoogle Scholar
  6. 6.
    Malcolm AJ, Schiller AL, Schneider-Stock R. Osteoblastoma. In: Fletcher CDM, Unni KK, Mertens F, editors. World Health Organization classification of tumours: pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press; 2002. p. 262–3.Google Scholar
  7. 7.
    Jundt G, Bertoni F, Unni KK, et al. Osteoblastoma. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. World Health Organization classifications of tumours: pathology and genetics of head and neck tumours. Lyon: IARC Press; 2005. p. 55–6.Google Scholar
  8. 8.
    Ohkubo T, Hernandez JC, Ooya K, Krutschkoff DJ. Aggressive osteoblastoma of the maxilla. Oral Surg Oral Med Oral Pathol. 1989;68:69–73.PubMedCrossRefGoogle Scholar
  9. 9.
    Filippi RZ, Swee RG, Unni KK. Epithelioid multinodular osteoblastoma: a clinicopathologic analysis of 26 cases. Am J Surg Pathol. 2007;31:1265–8.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC (outside the USA) 2012

Authors and Affiliations

  • Jennifer D. Britt
    • 1
  • Mark D. Murphey
    • 2
  • James T. Castle
    • 3
    Email author
  1. 1.Department Of Oral & Maxillofacial PathologyNaval Postgraduate Dental School, NMMPT&EBethesdaUSA
  2. 2.Musculoskeletal ImagingAmerican Institute for Radiologic Pathology (AIRP)Silver SpringUSA
  3. 3.Department of Anatomic PathologyNaval Medical Center PortsmouthPortsmouthUSA

Personalised recommendations