Skip to main content


Log in

Salivary Gland Tumor: A Review of 599 Cases in a Brazilian Population

  • Original Paper
  • Published:
Head and Neck Pathology Aims and scope Submit manuscript


Salivary gland tumors consist of a group of heterogeneous lesions with complex clinicopathological characteristics and distinct biological behaviors. Worldwide series show a contrast in the relative incidence of salivary gland tumors, with some discrepancies in clinicopathological data. The main aim of this study was to describe demographic characteristics of 599 cases in a population from Central Brazil over a 10-year period and compare these with other epidemiological studies. Benign tumors represented 78.3% of the cases. Women were the most affected (61%) and the male:female ratio was 1:1.6. Parotid gland tumors were the most frequent (68.5% of cases) and patient age ranged from 1 to 88 years-old (median of 45 years old). The most frequent tumors were pleomorphic adenomas (68.4%) and benign tumors were significantly more frequent in the parotid (75.9%), while malignant tumors were more frequent in the minor salivary glands (40%) (P < 0.05). In conclusion, women and the parotid gland were the most affected and pleomorphic adenoma was the most frequent lesion, followed by adenoid cystic carcinoma and Warthin’s tumor.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others


  1. Ellis GL, Auclair PL. Atlas of Tumor Pathology. Tumors of the Salivary Glands. Washington: AFIP; 1996.

    Google Scholar 

  2. Seifert G, Sobin LH. World health organization classification of tumours. Histopathological classification of tumors. Berlin, Germany: Springer-Verlag; 1991.

    Google Scholar 

  3. Ansari MH. Salivary gland tumors in an Iranian population: a retrospective study of 130 cases. J Oral Maxillofac Surg. 2007;65:2187–94.

    Article  PubMed  Google Scholar 

  4. Eveson JW, Cawson RA. Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution. J Pathol. 1985;146:51–8.

    Article  CAS  PubMed  Google Scholar 

  5. Spiro RH. Salivary neoplasms: overview of a 35-year experience with 2, 807 patients. Head Neck Surg. 1986;8:177–84.

    Article  CAS  PubMed  Google Scholar 

  6. Dardick I, Burford-Mason AP, Garlick DS, et al. The pathobiology of salivary gland. II. Morphological evaluation of acinic cell carcinomas in the parotid gland of male transgenic (MMTV/v-Ha-ras) mice as a model for human tumours. Virchows Arch A Pathol Anat Histopathol. 1992;421:105–13.

    Article  CAS  PubMed  Google Scholar 

  7. Satko I, Stanko P, Longauerová I. Salivary gland tumours treated in the stomatological clinics in Bratislava. J Craniomaxillofac Surg. 2000;28:56–61.

    CAS  PubMed  Google Scholar 

  8. Williams NP, Boyd DL, Choy L, et al. Salivary gland lesions: a Jamaican perspective. West Indian Med J. 2001;50:62–5.

    CAS  PubMed  Google Scholar 

  9. Vargas PA, Gerhard R, Araujo Filho VJ, et al. Salivary gland tumors in a Brazilian population: a retrospective study of 124 cases. Rev Hosp Clin Fac Med Sao Paulo. 2002;57:271–6.

    PubMed  Google Scholar 

  10. Ito FA, Ito K, Vargas PA, et al. Salivary gland tumors in a Brazilian population: a retrospective study of 496 cases. Int J Oral Maxillofac Surg. 2005;34:533–6.

    Article  CAS  PubMed  Google Scholar 

  11. Lima SS, Soares AF, de Amorim RF, et al. Epidemiologic profile of salivary gland neoplasms: analysis of 245 cases. Braz J Otorhinolaryngol. 2005;71:335–40.

    PubMed  Google Scholar 

  12. Al-Khateeb TH, Ababneh KT. Salivary tumors in north Jordanians: a descriptive study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103:e53–9.

    Article  PubMed  Google Scholar 

  13. Otoh EC, Johnson NW, Olasoji H, et al. Salivary gland neoplasms in Maiduguri, north-eastern Nigeria. Oral Dis. 2005;11:386–91.

    Article  CAS  PubMed  Google Scholar 

  14. Li LJ, Li Y, Wen YM, et al. Clinical analysis of salivary gland tumor cases in West China in past 50 years. Oral Oncol. 2008;44:187–92.

    Article  CAS  PubMed  Google Scholar 

  15. Kayembe MK, Kalengayi MM. Salivary gland tumors in Congo (Zaire). OdontoStomatol Tropicale. 2002;25:19–22.

    CAS  Google Scholar 

Download references


The authors would like to thank FAPEG, FUNAPE, CAPES, CNPq, FO/UFG and IPTSP/UFG for their financial support. The authors are also grateful to Lynne S. P. Brito for her technical support.

Author information

Authors and Affiliations


Corresponding author

Correspondence to Eneida Franco Vencio.

Rights and permissions

Reprints and permissions

About this article

Cite this article

de Oliveira, F.A., Duarte, E.C.B., Taveira, C.T. et al. Salivary Gland Tumor: A Review of 599 Cases in a Brazilian Population. Head and Neck Pathol 3, 271–275 (2009).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: