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Parathyroid adenoma is part of a spectrum of parathyroid proliferative disorder that includes parathyroid hyperplasia, parathyroid adenoma, and parathyroid carcinoma. Patients typically present with evidence of primary hyperparathyroidism with elevated serum calcium levels and elevated serum parathyroid hormone levels. Hyperparathyroidism is divided into primary, secondary, and tertiary hyperparathyroidism. Most parathyroid hyperplasia is the result of secondary hyperparathyroidism due to renal disease. Tertiary hyperparathyroidism is the autonomous secretion of parathyroid hormone in the setting of long-standing renal disease resulting in hypercalcemia. Eighty to 85 percent of primary hyperparathyroidism is caused by parathyroid adenoma followed by primary parathyroid hyperplasia (15%) and parathyroid carcinoma (5%).
Patients with primary hyperparathyroidism may present with clinical evidence of elevated serum calcium levels which include non-specific symptoms such as...
KeywordsPrimary Hyperparathyroidism Parathyroid Adenoma Parathyroid Carcinoma Parathyroid Neoplasm Parathyroid Hyperplasia
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