Abstract
We report backbone and side-chain resonance assignments of the Bright/ARID domain from the human JARID1B protein. These assignments provide a basis for the detailed structural investigation of the interaction between DNA and ARID domains.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Delaglio F, Grzesiek S, Vuister GW, Zhu G, Pfeifer J, Bax A (1995) NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J Biomol NMR 6:277–293. doi:10.1007/BF00197809
Goddard TD, Kneller DG SPARKY 3. University of California, San Francisco. http://www.cgl.ucsf.edu/home/sparky/
Lu PJ, Sundquist K, Baeckstrom D, Poulsom R, Hanby A, Meier-Ewert S, Jones T, Mitchell M, Pitha-Rowe P, Freemont P, Taylor-Papadimitriou J (1999) A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer. J Biol Chem 274:15633–15645. doi:10.1074/jbc.274.22.15633
Madsen B, Spencer-Dene B, Poulsom R, Hall D, Lu PJ, Scott K, Shaw AT, Burchell JM, Freemont P, Taylor-Papadimitriou J (2002) Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer. Mech Dev 119:S239–S246. doi:10.1016/S0925-4773(03)00123-0
Madsen B, Tarsounas M, Burchell JM, Hall D, Poulsom R, Taylor-Papadimitriou J (2003) PLU-1, a transcriptional repressor and putative testis-cancer antigen, has a specific expression and localisation pattern during meiosis. Chromosoma 112:124–132. doi:10.1007/s00412-003-0252-6
Patsialou A, Wilsker D, Moran E (2005) DNA-binding properties of ARID family proteins. Nucleic Acids Res 33:66–80. doi:10.1093/nar/gki145
Roesch A, Mueller AM, Stempfl T, Moehle C, Landthaler M, Vogt T (2008) RBP2-H1/JARID1B is a transcriptional regulator with a tumor suppressive potential in melanoma cells. Int J Cancer 122:1047–1057. doi:10.1002/ijc.23211
Scibetta AG, Santangelo S, Coleman J, Hall D, Chaplin T, Copier J, Catchpole S, Burchell J, Taylor-Papadimitriou J (2007) Functional analysis of the transcription repressor PLU-1/JARID1B. Mol Cell Biol 27:7220–7235. doi:10.1128/MCB.00274-07
Tu S, Teng YC, Yuan C, Wu YT, Chan MY, Cheng AN, Lin PH, Juan LJ, Tsai MD (2008) The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif. Nat Struct Mol Biol 15:419–421. doi:10.1038/nsmb.1400
Wishart DS, Sykes BD, Richards FM (1992) The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy. Biochemistry 31:1647–1651. doi:10.1021/bi00121a010
Xiang Y, Zhu Z, Han G, Ye X, Xu B, Peng Z, Ma Y, Yu Y, Lin H, Chen AP, Chen CD (2007) JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer. Proc Natl Acad Sci USA 104:19226–19231. doi:10.1073/pnas.0700735104
Yamane K, Tateishi K, Klose RJ, Fang J, Fabrizio LA, Erdjument-Bromage H, Taylor-Papadimitriou J, Tempst P, Zhang Y (2007) PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. Mol Cell 25:801–812. doi:10.1016/j.molcel.2007.03.001
Acknowledgments
We thank Prof. Chen DG and Mr. Xiang Y for providing human JARID1B-ARID gene. This work was supported by grants from the Natural Science Foundation of China (Nos. 30570352, 30730026), the Chinese Academy of Sciences (CAS) Knowledge Creative Program (No. KSCX2-YW-R-104), and the New Drug Basic Research Program of the Shanghai Institute of Materia Medica, CAS (No. 07G603N058).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Yao, W., Peng, Y., Chen, Q. et al. 1H, 13C, 15N backbone and side-chain resonance assignments of the Bright/ARID domain from the human histone demethylase JARID1B. Biomol NMR Assign 3, 85–87 (2009). https://doi.org/10.1007/s12104-009-9147-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12104-009-9147-7