Abstract
UbcH7 is a human E2 conjugating enzyme in the ubiquitin-dependent protein degradation pathway. The resonance assignments of UbcH7 will assist in elucidating the structural basis of interactions that occur within ubiquitination.
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Abbreviations
- RING:
-
Really interesting new gene
- HHARI:
-
Human homologue of Drosophila ariadne
- NMR:
-
Nuclear magnetic resonance
- HSQC:
-
Heteronuclear single quantum correlation
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Acknowledgments
The authors wish to thank Dr. Phillip Robinson and Dr. Helen Ardley for the UbcH7 plasmid. We would also like to thank Kathryn Barber for her technical support and Dr. Matthew Revington for his assistance in NMR data processing. This work was supported by grants from the Canadian Institutes of Health Research (CIHR), the Canada Research Chairs Program (G.S.S.), the CIHR Canada Graduate Scholarship (S.A.S.) and the Ontario Graduate Scholarship (S.A.S.).
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Serniwka, S.A., Shaw, G.S. 1H, 13C and 15N resonance assignments for the human E2 conjugating enzyme, UbcH7. Biomol NMR Assign 2, 21–23 (2008). https://doi.org/10.1007/s12104-007-9074-4
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DOI: https://doi.org/10.1007/s12104-007-9074-4