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Backbone assignment of human proliferating cell nuclear antigen

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Abstract

PCNA is an essential factor for DNA replication, repair, chromatin metabolism, and effector of cell-cycle regulatory signals. The assignment of backbone 1HN, 13Cα, 13CO, and 15N, and sidechain 13Cβ resonances of the human PCNA homotrimeric ring (∼90 kDa, 261 residues) is reported here.

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Acknowledgements

This work was funded in part by Ministerio de Educación y Ciencia of Spain grant GEN2003-28642 (FJB), European Union grant 3D-repertoire LSHG-CT-2005-512028 (FJB) and Comunidad Autónoma de Madrid grant BIPEDD-CM (RCO).

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Authors and Affiliations

  1. Structural and Computational Biology Programme, Spanish National Cancer Center (CNIO), C. Melchor Fernández Almagro 3, Madrid, 28029, Spain

    Ricardo Sánchez, Daniel Torres, Jesús Prieto & Ramón Campos-Olivas

  2. Structural Biology Unit, CIC bioGUNE, Bizkaia Technology Park, Building 801A, Derio, 48160, Spain

    Francisco J. Blanco

Authors
  1. Ricardo Sánchez
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  2. Daniel Torres
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  3. Jesús Prieto
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  4. Francisco J. Blanco
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  5. Ramón Campos-Olivas
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Corresponding authors

Correspondence to Francisco J. Blanco or Ramón Campos-Olivas.

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Sánchez, R., Torres, D., Prieto, J. et al. Backbone assignment of human proliferating cell nuclear antigen. Biomol NMR Assign 1, 245–247 (2007). https://doi.org/10.1007/s12104-007-9068-2

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  • DOI: https://doi.org/10.1007/s12104-007-9068-2

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