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Correlation of Plethysmograph Variability Index with Inferior Vena Cava Index in Spontaneously Breathing Neonates – A Cross Sectional Study

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Abstract

Inferior vena cava (IVC) indices are commonly used to assess the need for fluid bolus during shock. It needs expertise and is difficult to do during surgical procedures. Plethysmograph variability index (PVI) is a simpler non-invasive tool used to measure fluid responsiveness in adults. However, the data on PVI in neonates is limited. This cross-sectional observational study was done at a tertiary level NICU to correlate PVI and IVC among spontaneously breathing neonates. The PVI was documented using the Masimo Radical 7 pulse oximeter. The IVC collapsibility index (IVC CI) was determined by bedside ultrasound. The Spearman correlation coefficient was analyzed. The PVI showed strong positive correlation with IVC CI (rho = 0.64, 95% CI: 0.474–0.762) (p <0.001). Thus, PVI can be a useful tool for hemodynamic monitoring of neonates. However, further studies are needed before applying it to clinical use.

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Authors and Affiliations

  1. Department of Neonatology, Manipal Hospital, Bangalore-560017, Karnataka, India

    Vindhya Narayanaswamy, Venkatesh Harohalli A, Ravi Shankar Swamy & Karthik Nagesh N

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  1. Vindhya Narayanaswamy
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  2. Venkatesh Harohalli A
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  3. Ravi Shankar Swamy
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  4. Karthik Nagesh N
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Contributions

VN collected the data, analyzed the results and wrote the preliminary manuscript; KNN designed the study, analyzed results and revised the manuscript; VHA analyzed ultrasound images, data collection and revised the manuscript, and RSS helped in designing the study, data collection and revised the manuscript. KNN will act as guarantor for this manuscript.

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Correspondence to Karthik Nagesh N.

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Narayanaswamy, V., Harohalli A, V., Swamy, R.S. et al. Correlation of Plethysmograph Variability Index with Inferior Vena Cava Index in Spontaneously Breathing Neonates – A Cross Sectional Study. Indian J Pediatr 91, 81–83 (2024). https://doi.org/10.1007/s12098-023-04738-y

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  • DOI: https://doi.org/10.1007/s12098-023-04738-y

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