References
Kumar S, Navid A, Sharma R, Suthar R, Vyas S, Angurana SK. Acute necrotizing encephalopathy of childhood: a rare neurological manifestation of dengue. Ann Indian Acad Neurol. 2021;24:828–31.
Takia L, Patra N, Nallasamy K, et al. Acute necrotizing encephalopathy of childhood with H1N1 infection. J Pediatr Intensive Care. 2020;9:222–4.
Mizuguchi M, Hayashi M, Nakano I, et al. Concentric structure of thalamic lesions in acute necrotizing encephalopathy. Neuroradiology. 2002;44:489–93.
Wang X, Li Y, Deloria-Knoll M, et al. Global burden of acute lower respiratory infection associated with human metapneumovirus in children under 5 years in 2018: a systematic review and modelling study. Lancet Glob Health. 2021;9:e33–43.
Acknowledgements
Regional Virus Research and Diagnostic Laboratory (RVDRL), Department of Health Research (DHR), Ministry of Health and Family Welfare (MoHFW), Government of India (GoI) for carrying out the viral studies in the Department of Virology, PGIMER, Chandigarh.
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Supplementary Fig. S1
Axial T2-weighted (a), FLAIR (b and c), Susceptibility weighted images (SWI, d), Diffusion weighted (e and f, b = 1000 s/mm2), and Apparent diffusion coefficient (ADC, g and h) MRI brain images showing altered signal intensities with patchy diffusion restriction involving bilateral thalami, dorsal brainstem, external capsule/insula, mamillary bodies, and temporal lobes. In addition, multiple tiny punctuate hemorrhages are seen in thalami (d).
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Choudhary, I., KC, S., Kumar, P. et al. Acute Necrotizing Encephalopathy of Childhood Associated with Human Metapneumovirus. Indian J Pediatr 91, 203–204 (2024). https://doi.org/10.1007/s12098-023-04692-9
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DOI: https://doi.org/10.1007/s12098-023-04692-9