Abstract
Limited evidence shows minimal enteral nutrition (MEN) during therapeutic hypothermia (TH) in neonates to be feasible and have benefits of shorter time to full-feeds. This study aimed to assess the feasibility of MEN during TH. MEN was initiated after 12 h if there were no altered aspirates, abdominal distension, and inotrope requirement. The authors retrospectively analyzed the records from May 2017 to April 2022. The number of episodes of feed intolerance and the length of hospital stay were the key outcomes. A total of 99 neonates were fed during cooling. MEN could be initiated at a median duration (IQR) of 24 (24–30) h. There were 9 (9%) neonates with feed intolerance during TH. None had necrotizing enterocolitis. Ninety-two (93%) neonates were discharged, with a median hospital stay (IQR) of 9 d (6–15). Hence, MEN during TH is feasible and provides a rationale for future controlled trials.
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SS assisted in finalizing data collection tool, compiled data, statistical analysis, and drafted the initial manuscript; AK assisted in finalizing data collection tool, compiled data, assisted in data analysis, and gave critical inputs to the manuscript; ASA conceptualized the study, supervised data collection, assisted in data analysis, critical inputs to the manuscript; SD did data collection, and gave critical inputs to the manuscript; NNS conceptualized the study, assisted in finalizing data collection tool, did data collection, and approved the manuscript; PSV, SW, IVR, DS supervised data collection, assisted in data analysis, and gave critical inputs to the manuscript; PV supervised data collection, assisted in data analysis, and gave critical inputs to the manuscript. All authors approved the final manuscript and agreed to be accountable for all aspects of the work. ASA will act as the guarantor for this paper.
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Sharma, S., Kallesh, A., Aradhya, A.S. et al. Feasibility of Minimal Enteral Nutrition During Therapeutic Hypothermia for Perinatal Asphyxia: A Five-Year Multicenter Experience from South India. Indian J Pediatr 90, 513–515 (2023). https://doi.org/10.1007/s12098-022-04456-x
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DOI: https://doi.org/10.1007/s12098-022-04456-x