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Comparison of STOPS and SNAPPE-II in Predicting Neonatal Survival at Hospital Discharge: A Prospective, Multicentric, Observational Study

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Abstract

Objective

To compare SNAPPE-II and STOPS admission severity scores in neonates admitted to neonatal intensive care unit (NICU) with a gestational age of ≥ 33 wk.

Methods

In this multicenter, prospective, observational study, the sickness scoring was done on all the neonates at 12 h after admission to the NICUs. The scoring systems were compared by the area under the curve (AUC) on the receiver operating characteristics (ROC) curve.

Results

A total of 669 neonates with gestational age ≥ 33 wk (mortality rate: 2.4%), who were admitted to five participating NICUs within 24 h of birth, were included. Both SNAPPE-II and STOPS had the good discriminatory and predictive ability for mortality with AUCs of 0.965 [95% confidence interval (CI): 0.94–0.98] and 0.92 (95% CI: 0.87–0.99), respectively. The STOPS scoring system with a cutoff score ≥ 4 on the ROC curve had 85% accuracy, whereas the SNAPPE-II cutoff score ≥ 33 on the ROC curve had 94% accuracy in predicting mortality.

Conclusion

In infants with the gestational age of ≥ 33 wk, SNAPPE-II and STOPS showed similar predictive ability, but the STOPS score, being a simpler clinical tool, might be more useful in resource-limited settings.

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Authors and Affiliations

Authors

Contributions

VV, SM, VRK: Concept of the study; VV, SM, TPO, BS, BT: Design of study; VV, BT, BS, YAM, S Seth, S Siramshetty, VRK: Data acquisition; VV, SM, SD: Analysis; VV, SM, SD, TPO: Drafting of the work and revising the manuscript. All authors approved the final manuscript as submitted and agreed to be accountable for all aspects of the work. SM will act as the guarantor for this paper.

Corresponding author

Correspondence to Venkateshwarlu Vardhelli.

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IRB approval was obtained for the study and written informed consent was taken from all parents.

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Vardhelli, V., Seth, S., Mohammed, Y.A. et al. Comparison of STOPS and SNAPPE-II in Predicting Neonatal Survival at Hospital Discharge: A Prospective, Multicentric, Observational Study. Indian J Pediatr 90, 781–786 (2023). https://doi.org/10.1007/s12098-022-04330-w

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  • DOI: https://doi.org/10.1007/s12098-022-04330-w

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