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Recent Advances in Bronchopulmonary Dysplasia

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Abstract

Bronchopulmonary dysplasia (BPD) is a form of chronic lung disease that occurs in preterm infants, usually those receiving substantial respiratory support with either mechanical ventilation or supplementation with oxygen. The pathogenesis of BPD is multifactorial, and the clinical phenotype is variable. BPD is associated with substantial mortality and short- and long-term morbidity. The incidence of BPD has remained stable or increased, as advances in neonatal care have led to improved survival of more extremely preterm infants. Extensive basic science, translational, and clinical research focusing on BPD has improved the current understanding of the factors that contribute to BPD pathogenesis. However, despite a better understanding of its pathophysiology, BPD continues to be challenging to prevent and manage adequately. The current review aims to provide a clinically useful synopsis of evidence on the prevention and management of BPD in preterm infants.

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Authors and Affiliations

  1. Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA

    Vivek V. Shukla & Namasivayam Ambalavanan

  2. 176F, Suite 9380, Women and Infants Center, University of Alabama at Birmingham, Birmingham, AL, 35233, USA

    Namasivayam Ambalavanan

Authors
  1. Vivek V. Shukla
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  2. Namasivayam Ambalavanan
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Both authors drafted the initial manuscript and revised it, and generated the figures. NA will act as guarantor for this paper.

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Correspondence to Namasivayam Ambalavanan.

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Shukla, V.V., Ambalavanan, N. Recent Advances in Bronchopulmonary Dysplasia. Indian J Pediatr 88, 690–695 (2021). https://doi.org/10.1007/s12098-021-03766-w

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  • DOI: https://doi.org/10.1007/s12098-021-03766-w

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