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Goiter Prevalence and Interrelated Components from Coastal Karnataka

  • Avinash Shetty
  • Chythra R. Rao
  • Asha Kamath
  • Vibha SP
  • Sravan Kumar Reddy T
Original Article
  • 31 Downloads

Abstract

Objective

To assess prevalence of goiter and associated factors among school going children in Udupi district.

Methods

A school based cross-sectional survey was conducted among 6–12 year old children. A sample of 30 villages was selected from the entire district by probability proportionate to size. One school was then randomly selected from each of the 30 villages. Goiter was assessed clinically and was graded as per the recommended criteria of World Health Organization (WHO)/ United Nations Children’s Fund (UNICEF)/ International Council for the Control of Iodine Deficiency Disorders (ICCIDD). Salt and urine samples were collected from a subsample for iodine estimation.

Results

A total of 2703 children were examined. The mean (±SD) age of the participants was 9.6 y (±1.9). The overall prevalence of goiter in Udupi district was found to be 9.3% with 7.0% and 2.3% having grade 1 and grade 2 goiter respectively. Prevalence of goiter was significantly higher among females [153(11.1%)] as compared to males [98(7.4%)] (p = 0.001). Of the 543 salt samples analyzed, 379 (69.8%) salt samples had adequate salt iodine content (> 15 ppm); while among the children with goiter 32 (8.4%) had inadequate salt iodine. Median iodine value was 202.12 mcg/l among the 270 urine samples tested for iodine levels.

Conclusion

Goiter prevalence at 9.3% in the coastal district contributes to the endemicity of the public health problem. The district had adequate iodine nutrition based on median urinary iodine levels. Hence, other contributing factors for the persistence of endemic goiter need to be explored.

Keywords

Goiter School children Iodine deficiency Prevalence Urinary iodine 

Notes

Acknowledgements

The authors would like to acknowledge the Government of Karnataka for funding the project, the children who participated in the study and the support extended by the schools in conducting the survey. They would also like to thank the MSWs and survey team members from the Department of Community Medicine, Kasturba Medical College, Manipal for their support for the conduct of the study. They are thankful to the Biochemistry Department at Kasturba Medical College, Manipal for analysing the samples and providing timely results.

Contributions

AS, CRR, AK planned and supervised the study. VSP, SKRT collected the data, reviewed the literature and prepared the draft manuscript. AS provided critical inputs into the final version of manuscript. CRR, AK, VSP, SKRT analyzed the data and critically revised the manuscript for important intellectual content. AS will act as guarantor of study.

Compliance with Ethical Standards

Ethical Approval

“All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.” Institutional Ethical clearance was obtained from Ethics Committee (IEC) of Kasturba Medical College, Manipal (IEC: 922/2016). Informed consent was obtained from all individual participants included in the study.

Conflict of Interest

None.

Source of Funding

National Iodine Deficiency Disorders Control Programme (NIDDCP), Ministry of Health and Family Welfare, Karnataka.

References

  1. 1.
    World Health Organization. Effect and safety of salt iodization to prevent iodine deficiency disorders: a systematic review with meta-analyses. [Internet] 2014. Available at: http://apps.who.int/iris/bitstream/10665/148175/1/9789241508285_eng.pdf. Accessed 24 May 2017.
  2. 2.
    World Health Organization. Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programme managers. – 3rd ed [Internet]. Available at: http://apps.who.int/iris/bitstream/10665/43781/1/9789241595827_eng.pdf. Accessed 24 May 2017.
  3. 3.
    National Rural Health Mission IDD & Nutrition Cell Revised Policy Guidelines on National Iodine Deficiency Disorders Control Programme 2006. [Internet]. Available at: http://nrhm.gov.in/images/pdf/programmes/ndcp/niddcp/revised_guidelines.pdf. Accessed 24 May 2017.
  4. 4.
    Pandav CS, Yadav K, Srivastava R, Pandav R, Karmarkar MG. Iodine deficiency disorders (IDD) control in India. Indian J Med Res. 2013;138:418–33.PubMedPubMedCentralGoogle Scholar
  5. 5.
    Government of India. Ministry of Health & Family Welfare. National Iodine Deficiency Disorders Control Programme. Available at: http://dghs.gov.in/WriteReadData/userfiles/file/Annexure_IDD_I.pdf. Accessed 19 June 2017.
  6. 6.
    Kalra S, Unnikrishnan AG, Sahay R. The global burden of thyroid disease. Thyroid Res Pract. 2013;10:89–90.CrossRefGoogle Scholar
  7. 7.
    Indian National Science Academy. Micro-nutrient security for India– Priorities for research and action. [Internet] 2011. Available at: http://insaindia.res.in/pdf/Micronutrient-Complete.pdf. Accessed 19 Jun 2017.
  8. 8.
    Knowles JM, Garrett GS, Gorstein J, et al. Household coverage with adequately iodized salt varies greatly between countries and by residence type and socioeconomic status within countries: results from 10 national coverage surveys. J Nutr. 2017;147:1004S–14S.CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Sen TK, Das DK, Biswas AB, Chakrabarty I, Mukhopadhyay S, Roy R. Limited access to iodized salt among the poor and disadvantaged in north 24 Parganas district of West Bengal, India. J Health Popul Nutr. 2010;28:369–74.Google Scholar
  10. 10.
    World Health Organisation. Goitre as a determinant of prevalence and severity of Iodine deficiency disorders in populations [online] 2014. Available at: http://apps.who.int/iris/bitstream/10665/133706/1/WHO_NMH_NHD_EPG_14.5_eng.pdf. Accessed 28 June 2017.
  11. 11.
    Kliegman R, Stanton B, St. Geme JW, Schor NF, Behrman RE. Nelson Textbook of Pediatrics, 20th ed. PA: Elsevier; 2016.Google Scholar
  12. 12.
    Sridhar PV, Kamala CS. Iodine status and prevalence of goitre in school going children in rural area. J Clin Diagn Res. 2014;8:PC15–7.Google Scholar
  13. 13.
    Sinha AK, Sharma H, Panda PS, Chandrakar A, Pradhan SK, Dixit S. Prevalence of goitre, iodine uptake and salt iodization level in Mahasamund district of Chhattisgarh: a baseline study in Central India. Int J Res Med Sci. 2016;4:3590–4.CrossRefGoogle Scholar
  14. 14.
    Biradar MK, Manjunath M, Harish BR, Goud BN. Prevalence of iodine deficiency disorders among 6 to 12 years school children of Ramanagara district, Karnataka, India. Int J Community Med Public Health. 2016;3:166–9.CrossRefGoogle Scholar
  15. 15.
    Chaudhary C, Pathak R, Ahluwalia SK, Goel RK, Devgan S. Iodine deficiency disorder in children aged 6–12 years of Ambala. Haryana Indian Pediatr. 2013;50:587–9.CrossRefPubMedGoogle Scholar
  16. 16.
    Sareen N, Kapil U, Nambiar V, Pandey RM, Khenduja P. Iodine nutritional status in Uttarakhand state, India. Indian J Endocrinol Metab. 2016;20:171.Google Scholar
  17. 17.
    Gupta VP, Bharat PP, Kamboj A, Paul B, Mohapatra SC. Prevalence of goitre among primary school children in the Mewat area of Haryana. J Community Health Manag. 2016;3:67–9.CrossRefGoogle Scholar
  18. 18.
    Sinha AK, Soni GP, Khes SP, Verma AR. A study of prevalence of iodine deficiency disorders among 6-12 years children of Rajnandgaon District of Chhattisgarh. Int J Health Sci Res. 2016;6:25–31.Google Scholar
  19. 19.
    Gupta RK, Langer B, Raina SK, Kumari R, Jan R, Rani R. Goiter prevalence in school-going children: a cross-sectional study in two border districts of sub-Himalayan Jammu and Kashmir. J Family Med Prim Care. 2016;5:825–8.CrossRefPubMedPubMedCentralGoogle Scholar
  20. 20.
    Kamath V, Jacob G, Agrawal A, Kamath A, Shenoy R. Prevalence of goitre and its associated factors in a coastal district of Karnataka. Indian J Community Health. [Internet]. 31 Dec 2015. Available at: http://www.iapsmupuk.org/journal/index.php/IJCH/article/view/626. Accessed 12 July 2018.
  21. 21.
    Chandra AK, Debnath A, Tripathy S, et al. Environmental factors other than iodine deficiency in the pathogenesis of endemic goiter in the basin of river ganga and bay of Bengal, India. BLDE Univ J Health Sci. 2016;1:33–8.Google Scholar
  22. 22.
    Mesele M, Degu G, Gebrehiwot H. Prevalence and associated factors of goiter among rural children aged 6-12 years old in Northwest Ethiopia, cross-sectional study. BMC Public Health. 2014;14:130.CrossRefPubMedPubMedCentralGoogle Scholar
  23. 23.
    Khan SMS, Mahjabeen R, Masoodi MA, Kauser J, Nabi S. Prevalence of goiter among primary school children of Kulgam District, Jammu & Kashmir, India. Acad Med J India. 2014;2:18–21.Google Scholar
  24. 24.
    World Health Organization. Urinary iodine concentrations for determining iodine status in populations [online] 2013. Available at: http://apps.who.int/iris/bitstream/10665/85972/1/WHO_NMH_NHD_EPG_13.1_eng.pdf. Accessed 28 June 2017.
  25. 25.
    Bhat IA, Pandit IM, Mudassar S. Study on prevalence of iodine deficiency disorder and salt consumption patterns in Jammu region. Indian J Community Med. 2008;33:11–4.CrossRefPubMedPubMedCentralGoogle Scholar
  26. 26.
    Sharma LK, Hossen S. Knowledge, attitude and practices of households on iodized salt at urban slums in Dhaka City [online]. 2016. Available at: http://himachalcampus.pibm.in/research-journals/research-paper-4.html. Accessed 28 June 2017.
  27. 27.
    Kamath R, Bhat V, Rao RS, Das A, KS G, Kamath A. Prevalence of goiter in rural area of Belgaum district, Karnataka. Indian J Community Med. 2009;34:48–51.Google Scholar
  28. 28.
    Singh R, Raghuvanshi RS. Effect of household storage practices on iodine content of iodized salt. Asian J Home Sci. 2014;9:481–3.CrossRefGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2018

Authors and Affiliations

  1. 1.Department of Community Medicine, Kasturba Medical College (KMC)Manipal Academy of Higher EducationManipalIndia
  2. 2.Department of Statistics, PSPH, MAHEManipalIndia

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