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The Indian Journal of Pediatrics

, Volume 85, Issue 12, pp 1132–1133 | Cite as

Autism and Allergy – Are They Linked?

  • Neeraj Gupta
  • Anil Sachdev
  • Dhiren Gupta
  • Suresh Gupta
  • Deepak Gupta
  • Jalnidhi Nanavati
Scientific Letter
  • 63 Downloads

Abbreviations

ADHD

Attention Deficit Hyperactivity Disorder

ASD

Autism Spectrum Disorders

BBB

Blood Brain Barrier

DSM5

Diagnostic and Statistical Manual of Mental Disorders, 5th Edition

EEG

Electroencephalogram

IgE

Immunoglobulin E

IL

InterLeukin

IU

International Units

MC

Mast cell

mg

milligram

ml

milliliter

MRI

Magnetic Resonance Imaging

SPT

Skin Prick Test

Th cells

T helper cells

TNF

Tumor Necrosis Factor

Notes

Authors’ Contributions

NG performed the allergy test, was involved in clinical management of allergy and will act as guarantor for this paper. He drafted the initial manuscript; AS, DG and SG critically reviewed the manuscript for important intellectual content; DG and JN were involved in clinical management of autism. They reviewed and revised the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.

Compliance with Ethical Standards

Conflict of Interest

None.

References

  1. 1.
    Theoharides TC, Tsilioni I, Patel AB, Doyle R. Atopic diseases and inflammation of the brain in the pathogenesis of autism spectrum disorders. Transl Psychiatry. 2016;6:e844.CrossRefGoogle Scholar
  2. 2.
    Theoharides TC, Valent P, Akin C. Mast cells, mastocytosis, and related disorders. N Engl J Med. 2015;373:163–72.CrossRefGoogle Scholar
  3. 3.
    Theoharides TC, Stewart JM, Panagiotidou S, Melamed I. Mast cells, brain inflammation and autism. Eur J Pharmacol. 2016;778:96–102.CrossRefGoogle Scholar
  4. 4.
    Theoharides TC, Stewart JM, Hatziagelaki E, Kolaitis G. Brain “fog”, inflammation and obesity: key aspects of neuropsychiatric disorders improved by luteolin. Front Neurosci. 2015;9:225.CrossRefGoogle Scholar
  5. 5.
    Kalkman HO, Microglia FD. M2A polarization as potential link between food allergy and autism spectrum disorders. Pharmaceuticals (Basel). 2017;10:E95.CrossRefGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2018

Authors and Affiliations

  1. 1.Department of Pediatrics, Institute of Child HealthSir Ganga Ram HospitalNew DelhiIndia
  2. 2.Department of Pediatric PsychiatrySir Ganga Ram HospitalNew DelhiIndia

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