The Indian Journal of Pediatrics

, Volume 85, Issue 9, pp 718–722 | Cite as

‘Quality of Life’ of Parents of Children Suffering from Pediatric Malignancies in a Low Income Setting

  • Vibha Sanjay Bafna
  • Tanvi Ajay BafnaEmail author
  • Abhilasha Sampagar
  • Sunita Raman Rupavataram
Original Article



To evaluate the impact of pediatric malignancies on quality of life (QOL) and psychological status of parents and to correlate it with well-matched controls and socioeconomic status.


A prospective comparative cross-sectional study was conducted. Seventy parents of children diagnosed with pediatric malignancies within the last three months were enrolled in the study group (SG) and 50 matched parents of healthy children as the control group (CG). Assessment was done by WHOQOL-BREF questionnaire, Depression Anxiety Stress Score (DASS) scale and Kuppuswamy scale. Data analysis was done by using Statistical Package for social sciences (SPSS) version 20.0. p value <0.05 considered as significant.


Mean score of QOL for SG in physical health domain (D1), psychological health (D2), social relationships (D3) and environment health (D4) was 48.64, 43.07, 47.36, and 40.58 respectively whereas that of CG was 79.38, 76.32, 80.58 and 72.86 respectively and the difference was statistically significant (p value <0.001). The environmental domain (D4) had the lowest mean score amongst all domains in the SG. QOL was maximally affected by the parameter sleep, depression, personal relationship and lack of information in the respective domains. Mean depression, anxiety and stress score of SG was 23.43, 20.33, 23.56 respectively whereas that of the CG was 7.1, 8.06 and 8.54 respectively and this was statistically significant (p value <0.001). The QOL of SG in D1 for the lower socioeconomic class was 48.86 and for the upper class was 63 and this difference was statistically significant (p value <0.015). Similarly in D2 and D4 the QOL scores went higher with the socioeconomic class and this was statistically significant (p value < 0.007 and p value <0.030 respectively).


SG had poorer QOL and were significantly more depressed, anxious and stressed. It is concluded that effective interventions are needed to aid these families to improve outcomes by delivering the benefit of vastly improved therapeutic strategies in this field.


Quality of life Pediatric malignancies Depression Anxiety Stress 



The authors are thankful to Department of Pediatrics, Bharati Vidyapeeth Medical College and Hospital, Pune. A special thanks to statistician, Dr. M. G. Sayyad.


VSB: Conceptualized and designed the study, gave critical inputs and approved the final version of the article; TAB; Collected the data, wrote the primary draft of the article and data analysis; AS: Collected the data and data analysis; SRR: Helped to choose the questionnaires for the study. Dr. Sanjay Lalwani, Professor and Head of Department of Peadiatrics of Bharati Vidyapeeth University Medical College, Pune and Medical Director and Vice Principle of Bharati Vidyapeeth University Medical College, Pune will act as guarantor for this paper.

Compliance with Ethical Standards

Conflict of Interest


Source of Funding

Indian Council of Medical Research (2015–00195).


  1. 1.
    Arora RS, Eden TO, Kapoor G. Epidemiology of childhood cancer in India. Indian J Cancer. 2009;46:264–73.CrossRefPubMedGoogle Scholar
  2. 2.
    Reis LA, Eisner MP, Kosary CL, et al. SEER cancer statistics review, 1973-1998. National Cancer Institute; 2001. Available at:
  3. 3.
    Kohlsdorf M, Costa Junior ÁL. Psychosocial impact of pediatric cancer on parents: a literature review. Paidéia (RibeirãoPreto). 2012;22:119–29.CrossRefGoogle Scholar
  4. 4.
    Development of the World Health Organization WHOQOL-BREF Quality of Life Assessment. Psychological Medicine. Cambridge University Press; 1998;28. p. 551–8.Google Scholar
  5. 5. Depression Anxiety Stress Scales - DASS. [online]. 2017. Available at: Accessed 22 Oct 2017.
  6. 6.
    Kuppuswamy B. Manual of socioeconomic status (urban). 1st ed. Delhi: Manasayan; 1981. p. 66–72.Google Scholar
  7. 7.
    Batra P, Kumar B, Gomber S, Bhatia MS. Assessment of quality of life during treatment of pediatric oncology patients. Indian J Public Health. 2014;58:168–73.CrossRefPubMedGoogle Scholar
  8. 8.
    Klassen AF, Klassen R, Dix D, et al. Impact of caring for a child with cancer on parents’ health-related quality of life. J Clin Oncol. 2008;26:5884–9.CrossRefPubMedGoogle Scholar
  9. 9.
    Eyigor S, Karapolat H, Yesil H, Kantar M. The quality of life and psychological status of mothers of hospitalized pediatric oncology patients. Pediatr Hematol Oncol. 2011;28:428–38.CrossRefPubMedGoogle Scholar
  10. 10.
    Sharghi A, Karbakhsh M, Nabaei B, Meysamie A, Farrokhi A. Depression in mothers of children with thalassemia blood malignancies: a study from Iran. Clin Pract Epidemol Mental Health. 2006;2:27.CrossRefGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2018

Authors and Affiliations

  • Vibha Sanjay Bafna
    • 1
  • Tanvi Ajay Bafna
    • 1
    Email author
  • Abhilasha Sampagar
    • 1
  • Sunita Raman Rupavataram
    • 1
  1. 1.Department of PediatricsBharati Vidyapeeth Deemed University Medical CollegePuneIndia

Personalised recommendations