Advertisement

The Indian Journal of Pediatrics

, Volume 85, Issue 9, pp 797–799 | Cite as

Streptococcus pneumoniae-associated Hemolytic Uremic Syndrome

  • Suresh Kumar Angurana
  • Ankit Mehta
  • Triptee Agrawal
  • Karthi Nallasamy
  • Muralidharan Jayashree
Scientific Letter
  • 126 Downloads

To the Editor: Hemolytic uremic syndrome (HUS) is a common cause of acute kidney injury (AKI) in young children and is characterized by triad of microangiopathic hemolytic anemia (MAHA), thrombocytopenia, and AKI. Diarrhea-associated/typical HUS is the commonest (80-90%) cause of HUS in children (caused by enterohemorrhagic Escherichia coli O157:H7) [1, 2]. Though rarely reported from India, Streptococcus pneumoniae-associated HUS is well described from different parts of the world [3, 4, 5].

An 11-mo-boy presented with fever, cough, and rapid breathing for 7 d; and decreased urine output for 1 d. He had tachycardia, tachypnea, well palpable pulses, blood pressure 80/50 mmHg, and severe pallor; subcostal and intercostal retractions, decreased chest movements on right side; and dull note, decreased air entry, bronchial breathing, and crepitations over right infraclavicular, mammary, and infraaxillary area. Investigations are shown in Fig. 1 and Tables 1 and 2. Diagnosis of Streptococcus...

Notes

Compliance with Ethical Standards

Conflict of Interest

None.

References

  1. 1.
    Copelovitch L, Kaplan BS. Streptococcus pneumoniae-associated hemolytic uremic syndrome. Pediatr Nephrol. 2008;23:1951–6.CrossRefPubMedGoogle Scholar
  2. 2.
    Banerjee S. Hemolytic uremic syndrome. Indian Pediatr. 2009;46:1075–84.PubMedGoogle Scholar
  3. 3.
    Banerjee R, Hersh AL, Newland J, et al. Streptococcus pneumoniae-associated hemolytic uremic syndrome among children in North America. Pediatr Infect Dis J. 2011;30:736–9.CrossRefPubMedGoogle Scholar
  4. 4.
    Lee CS, Chen MJ, Chiou YH, Shen CF, Wu CY, Chiou YY. Invasive pneumococcal pneumonia is the major cause of paediatric haemolytic-uraemic syndrome in Taiwan. Nephrology (Carlton). 2012;17:48–52.CrossRefGoogle Scholar
  5. 5.
    Loupiac A, Elayan A, Cailliez M, et al. Diagnosis of Streptococcus pneumoniae-associated hemolytic uremic syndrome. Pediatr Infect Dis J. 2013;32:1045–9.CrossRefPubMedGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2018

Authors and Affiliations

  • Suresh Kumar Angurana
    • 1
  • Ankit Mehta
    • 1
  • Triptee Agrawal
    • 1
  • Karthi Nallasamy
    • 1
  • Muralidharan Jayashree
    • 1
  1. 1.Department of Pediatrics, Advanced Pediatrics CentrePostgraduate Institute of Medical Education and Research (PGIMER)ChandigarhIndia

Personalised recommendations