TP53 Mutation, MYCN Amplification, and Large Cell/Anaplastic Histology in Medulloblastoma

  • Anirban Das
  • Lateef Zameer
  • Sushant Vinarkar
  • Manish Singh
  • Mayur Parihar
  • Neeraj Arora
  • Aditi Chandra
  • Rimpa Basu Achari
Scientific Letter

Notes

Acknowledgements

The authors would like to thank Dr. Revathi Rajagopal, Department of Pediatrics, University of Malaya, Malaysia, for her inputs in the management of this patient.

Compliance with Ethical Standards

Conflict of Interest

None.

Source of Funding

None.

References

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    Schwalbe EC, Lindsey JC, Nakjang S, et al. Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study. Lancet Oncol. 2017 May 22. https://doi.org/10.1016/S1470-2045(17)30243-7. [Epub ahead of print].
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    Zhukova N, Ramaswamy V, Remke M, et al. WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma. Acta Neuropathol Commun. 2014;2:174.CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2017

Authors and Affiliations

  1. 1.Department of Pediatric Haematology/OncologyTata Medical CentreKolkataIndia
  2. 2.Department of HistopathologyTata Medical CentreKolkataIndia
  3. 3.Department of Molecular PathologyTata Medical CentreKolkataIndia
  4. 4.Department of CytogeneticsTata Medical CentreKolkataIndia
  5. 5.Department of RadiologyTata Medical CentreKolkataIndia
  6. 6.Department of Radiation OncologyTata Medical CentreKolkataIndia

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