Prevalence of Parvovirus B19V in Hematological Malignancies and Chronic Anemia
To the Editor: The present study was planned to estimate the prevalence of human Parvovirus B19 (B19V) infection in children suffering with hematological malignancies or chronic anemia. Such hospitalized children (<15 y) were enrolled consecutively from 2011 through 2014. King George’s Medical University’s institutional ethical clearance was obtained (no.52 E.C.M.IIA/P6). Anti B19V IgG and IgM antibodies (ELISA kits by NovaTech Immunodiagnostica, Dietzenbach, Germany) and B19V DNA (by real time PCR ) were estimated in serum samples of enrolled patients. Relevant laboratory parameters were noted from hospital records of cases. Statistical analysis was done using GraphPad Prism Version 5.
Compliance with Ethical Standards
Conflict of Interest
Source of Funding
We acknowledge financial support from Indian Council of Medical Research, New Delhi, India, for providing funding (grant no. 5/8/7/17/2010-ECD-1).