Congenital Fatal Diarrhea in Newborns
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Microvillus inclusion disease is a rare autosomal recessive disorder of intestinal epithelium causing intractable secretary diarrhea in the first two months of life and about 140 cases have been reported worldwide till now. Here authors report 2 cases of Microvillus inclusion disease (MVID) diagnosed in neonates by electron microscopy study of small intestinal biopsy.
KeywordsMicrovillus inclusion disease Neonatal diarrhea Small bowel biopsy
The authors acknowledge Dr. Anna B. Pulimood, Christian Medical College, Vellore for helping them in arriving at the diagnosis.
SL, MBS, SB: managed the baby; SL reviewed the literature and drafted the initial version of the manuscript; MBS, CNK, SB: contributed to literature review and critically revised the manuscript; SB did the duodenal mucosal biopsy. All the authors contributed to drafting of the manuscript and approved the final version of the manuscript. MBS will act as guarantor for the paper.
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