The Indian Journal of Pediatrics

, Volume 84, Issue 12, pp 953–954 | Cite as

Congenital Fatal Diarrhea in Newborns

  • Swapna Lingaldinna
  • Mangala Bharathi Sundaram
  • C. N. Kamalarathnam
  • Sumathi Bavanandam
Clinical Brief


Microvillus inclusion disease is a rare autosomal recessive disorder of intestinal epithelium causing intractable secretary diarrhea in the first two months of life and about 140 cases have been reported worldwide till now. Here authors report 2 cases of Microvillus inclusion disease (MVID) diagnosed in neonates by electron microscopy study of small intestinal biopsy.


Microvillus inclusion disease Neonatal diarrhea Small bowel biopsy 



The authors acknowledge Dr. Anna B. Pulimood, Christian Medical College, Vellore for helping them in arriving at the diagnosis.


SL, MBS, SB: managed the baby; SL reviewed the literature and drafted the initial version of the manuscript; MBS, CNK, SB: contributed to literature review and critically revised the manuscript; SB did the duodenal mucosal biopsy. All the authors contributed to drafting of the manuscript and approved the final version of the manuscript. MBS will act as guarantor for the paper.

Compliance with Ethical Standards

Conflict of Interest


Source of Funding



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Copyright information

© Dr. K C Chaudhuri Foundation 2017

Authors and Affiliations

  • Swapna Lingaldinna
    • 1
  • Mangala Bharathi Sundaram
    • 1
  • C. N. Kamalarathnam
    • 1
  • Sumathi Bavanandam
    • 2
  1. 1.Department of NeonatologyInstitute of Child Health and Hospital for ChildrenChennai-8India
  2. 2.Department of Pediatric GastroenterologyInstitute of Child Health and Hospital for ChildrenChennai-8India

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