The Indian Journal of Pediatrics

, Volume 84, Issue 6, pp 494–495 | Cite as

Novel Mutation in SH2 Domain of STAT3 (p.M660T) in Hyper-IgE Syndrome with Sterno-Clavicular and Paravertebral Abscesses

  • Biman Saikia
  • Shubham Goel
  • Deepti Suri
  • Ranjana W. Minz
  • Amit Rawat
  • Surjit Singh
Scientific Letter


  1. 1.
    Grimbacher B, Holland SM, Puck JM. Hyper-IgE syndromes. Immunol Rev. 2005;203:244–50.CrossRefPubMedGoogle Scholar
  2. 2.
    Giacomelli M, Tamassia N, Moratto D, et al. SH2-domain mutations in STAT3 in hyper-IgE syndrome patients result in impairment of IL-10 function. Eur J Immunol. 2011;41:3075–84.CrossRefPubMedGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2017

Authors and Affiliations

  1. 1.Department of ImmunopathologyPostgraduate Institute of Medical Education and ResearchChandigarhIndia
  2. 2.Department of PediatricsPostgraduate Institute of Medical Education and ResearchChandigarhIndia

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