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Sulfonylurea Poisoning in a Healthy Toddler

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Abstract

Ingestion of sulfonylureas is life-threatening in toddlers and children due to its strong and prolonged hypoglycemic effect. The authors present a 15-mo-old boy with accidental ingestion of Glipizide who presented with encephalopathy, seizure and severe hypoglycemia. The management included parenteral dextrose and octreotide administration to maintain euglycemia, followed by complete neurological recovery within 24 h. Sulphonylurea intoxication should be considered in previously healthy toddlers and children presenting with hypoglycemia especially if any caregiver is on sulfonylurea drugs.

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Contributions

SK: Managed patient, reviewed the literature and drafted the manuscript; AC and MA: Patient management; VG: Supervised patient management; JM: Supervised patient management and critically reviewed the manuscript; SCS: Critically reviewed the manuscript. JM will act as guarantor for the paper.

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Correspondence to Jayashree Muralidharan.

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Kumar, S., Choudhary, A., Ali, M. et al. Sulfonylurea Poisoning in a Healthy Toddler. Indian J Pediatr 84, 147–149 (2017). https://doi.org/10.1007/s12098-016-2249-1

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  • DOI: https://doi.org/10.1007/s12098-016-2249-1

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