Skip to main content
Log in

Reversible MRI Changes in an Infant with Epileptic Spasms on Low Dose Vigabatrin

  • Picture of the Month
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Pearl PL, Vezina LG, Saneto RP, et al. Cerebral MRI abnormalities associated with vigabatrin therapy. Epilepsia. 2009;50:184–94.

    Article  CAS  PubMed  Google Scholar 

  2. Wheless JW, Carmant L, Bebin M, et al. Magnetic resonance imaging abnormalities associated with vigabatrin in patients with epilepsy. Epilepsia. 2009;50:195–205.

    Article  CAS  PubMed  Google Scholar 

  3. Fong CY, Osborne JP, Edwards SW, et al. An investigation into the relationship between vigabatrin, movement disorders, and brain magnetic resonance imaging abnormalities in children with infantile spasms. Dev Med Child Neurol. 2013;55:862–7.

    Article  PubMed  Google Scholar 

  4. Simao GN, Zarei Mahmoodabadi S, Snead OC, Go C, Widjaja E. Abnormal axial diffusivity in the deep gray nuclei and dorsal brain stem in infantile spasm treated with vigabatrin. AJNR Am J Neuroradiol. 2011;32:199–203.

    CAS  PubMed  Google Scholar 

Download references

Contributions

PJ and RA provided the clinical care to the patient. VK provided the radiological inputs. PJ drafted the manuscript which was read and approved by all the authors, and will act as guarantor for the paper.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Puneet Jain.

Ethics declarations

Informed consent was taken from the parents for publication of the case report.

Conflict of Interest

None.

Source of Funding

None.

Appendix

Appendix

The genes covered in the panel are ARX, SLC2A1, STXBP1, SPTAN1, SCN1A, KCNQ2, ARHGEF9, PNKP, SCN2A, SCN8A, PLCB1, ALDH7A1, MTHFR, PMM2 and ADSL.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Jain, P., Alwadhi, R. & Kumar, V. Reversible MRI Changes in an Infant with Epileptic Spasms on Low Dose Vigabatrin. Indian J Pediatr 83, 1049–1050 (2016). https://doi.org/10.1007/s12098-015-2020-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12098-015-2020-z

Keywords

Navigation