Skip to main content

Advertisement

Log in

Vesiculobullous Disorders in Children

  • Original Article
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Objective

To study the frequency and clinical pattern of vesiculobullous disorders in children.

Methods

A retrospective chart review of all children diagnosed with vesiculobullous disorders over a period of 36 mo from January 2011 through December 2013 was performed. All children 18 y and below were included in the study.

Results

A total of 213 children presenting with vesiculobullous lesions were examined during the study period. Vesiculobullous disorders constituted 3.6 % of the total 5889 dermatoses seen during this period. The most common vesiculobullous disorder in children was infections (129, 60.6 %), followed by genodermatoses (35, 16.4 %), inflammatory disorders (33, 15.5 %), drug reaction (7, 3.3 %) and trauma (5, 2.3 %). Autoimmune and metabolic disorders constituted 1.4 % (three children) and 0.5 % (one child) respectively.

Conclusions

This study highlights the varied spectrum of vesiculobullous disorders seen in the pediatric population. Cutaneous infections and inherited disorders were the most common disorders observed in the present study.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Wu H, Schapiro B, Harrist TJ. Noninfectious vesiculobullous and vesiculopustular diseases. In: Elder DE, editor. Lever’s histopathology of the skin. Philadelphia: Lippincott, Williams and Wilkins; 2005. p. 243–91.

  2. Rico MJ. Differential diagnosis of vesiculobullous lesions. In: Harper J, Oranje A, Prose N, editors. Textbook of pediatric dermatology. Oxford: Blackwell Publishing; 2006. p. 823–30.

    Google Scholar 

  3. Sayal SK, Bal AS, Gupta CM. Pattern of skin diseases in pediatric age group and adolescents. Indian J Dermatol Venereol Leprol. 1998;64:117–9.

    CAS  PubMed  Google Scholar 

  4. Sardana K, Mahajan S, Sarkar R, Mendiratta V. The spectrum of skin disease among Indian children. Pediatr Dermatol. 2009;26:6–13.

    Article  PubMed  Google Scholar 

  5. Karthikeyan K, Thappa DM, Jeevenkumar B. Pattern of pediatric dermatoses in a referral centre in south India. Indian Pediatr. 2004;41:373–7.

    PubMed  Google Scholar 

  6. KasHyap S, Verma GK. Hand-foot-mouth-disease: outbreak in Shimla. Indian Pediatr. 2014;51:155.

    Article  PubMed  Google Scholar 

  7. Kar BR, Dwibedi B, Kar SK. Outbreak of hand foot and mouth disease in Bhubaneswar, Odisha. Indian Pediatr. 2013;50:139–42.

    Article  PubMed  Google Scholar 

  8. Ghosh SK, Bandyopadhyay D, Ghosh A, Dutta A, Biswas S, Mandal RK, et al. Mucocutaneous features of hand, foot, and mouth disease: a reappraisal from an outbreak in the city of Kolkata. Indian J Dermatol Venereol Leprol. 2010;76:564–6.

    Article  PubMed  Google Scholar 

  9. Fabiano V, Dilillo D, Mauri S, Vivaldo T, Gazzarri A, Zuccotti GV. Herpes zoster in an immunocompetent boy following intrauterine exposure to varicella-zoster virus. Cutis. 2013;91:127–8, 140.

    PubMed  Google Scholar 

  10. Weinmann S, Chun C, Schmid DS, Roberts M, Vandermeer M, Riedlinger K, et al. Incidence and clinical characteristics of herpes zoster among children in the varicella vaccine era, 2005–2009. J Infect Dis. 2013;208:1859–68.

    Article  PubMed  Google Scholar 

  11. Al-Ghamdi KM. A retrospective study of some clinical and epidemiological features of impetigo patients seen in dermatology clinic in the eastern province of Saudi Arabia. J Fam Community Med. 2006;13:31–4.

    Google Scholar 

  12. Fine JD, Johnson LB, Suchindran C, Moshell A, Gedde-Dahl T Jr. The epidemiology of inherited epidermolysis bulllosa: findings in the US, Canadian and European study populations. In: Fine JD, Bauer EA, Mc Guire J, Moshell A, editors. Clinical, epidemiological and laboratory advances, and the findings of the national epidermolysis bullosa registry. Baltimore: John’s Hopkings University Press; 1999. p. 101–13.

  13. Sarkar R, Bansal S, Garg VK. Epidermolysis bullosa: where do we stand? Indian J Dermatol Venereol Leprol. 2011;77:431–8.

    Article  PubMed  Google Scholar 

  14. Banerjee S, Gangopadhyay DN, Jana S, Chanda M. Seasonal variation in pediatric dermatoses. Indian J Dermatol. 2010;55:44–6.

    Article  PubMed Central  PubMed  Google Scholar 

  15. Gelmetti CM. Pompholyx. In: Irvine AD, Hoeger PH, Yan AC, editors. Harper’s textbook of pediatric dermatology. Oxford: Blackwell Publishing; 2011. p. 39.1–39.5.

  16. Sacchidanand S, Sahana MS, Asha GS, Shilpa K. Pattern of pediatric dermatosis at a referral centre. Indian J Pediatr. 2014;81:375–80.

    Article  CAS  PubMed  Google Scholar 

  17. Singh S, Mann BK. Insect bite reactions. Indian J Dermatol Venereol Leprol. 2013;79:151–64.

    Article  PubMed  Google Scholar 

  18. Kar S, Dongre A, Krishnan A, Godse S, Singh N. Epidemiological study of insect bite reactions from central India. Indian J Dermatol. 2013;58:337–41.

    Article  PubMed Central  PubMed  Google Scholar 

  19. Sarkar R, Basu S, Patwari AK, Sharma RC, Dutta AK, Sardana K. An appraisal of pediatric dermatological emergencies. Indian Pediatr. 2000;37:425–9.

    CAS  PubMed  Google Scholar 

  20. Letko E, Papaliodis DN, Papaliodis GN, Daoud YJ, Ahmed AR, Foster CS. Steven-Johnson syndrome and toxic epidermal necrolysis in children: a review of literature. Ann Allergy Asthma Immunol. 2005;94:419–36.

    Article  PubMed  Google Scholar 

  21. Lara-Corrales I, Pope E. Autoimmune blistering diseases in children. Semin Cutan Med Surg. 2010;29:85–91.

    Article  CAS  PubMed  Google Scholar 

Download references

Contributions

SMS: Concept, design, literature search, manuscript preparation; PKS: Data analysis; RH: Manuscript editing and review. RH will act as guarantor for this paper.

Conflict of Interest

None.

Source of Funding

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sahana M. Srinivas.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Srinivas, S.M., Sheth, P.K. & Hiremagalore, R. Vesiculobullous Disorders in Children. Indian J Pediatr 82, 805–808 (2015). https://doi.org/10.1007/s12098-015-1708-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12098-015-1708-4

Keywords

Navigation