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The Unforeseen Toll of Birth Defects and their Economic Burden at a Tertiary Care Public Institute in Mumbai

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Abstract

Objectives

To determine the proportion of patients with birth defects receiving indoor medical care and the economic burden incurred by the Institution in terms of cost of hospitalization.

Methods

This single center, prospective, observational study recruited children >28 d and <12 y of age with birth defect(s) not attributable to an acquired disease. Demographic data, maternal and antenatal data, nature of the defect and information about current and past hospitalization were recorded. Economic burden was estimated by computing bed charges and daily costs incurred by the Institution.

Results

Ninety-eight children (mean age was 3.18 y, M : F ratio was 2.4:1) with 268 birth defects represented 13 % of indoor admissions. The cardiovascular system was involved in 42.9 %. The defect was isolated in 58.2 % of cases and 41.8 % (9.2 % having Down syndrome) had multiple defects. Mean duration of hospital stay (11.23 d) of the birth defect cohort was significantly more (p value = 0.0005) than other children (7.81 d). Average cost of stay for those with birth defects (18.3 % of the total cost) and other indoor patients was INR 23,481 and INR 16,328 respectively.

Conclusions

Birth defects are an emerging burden in referral centers, incurring one-fifth of the hospital expenditure, partly due to increased length of stay. The figure is an underestimate as the expenses are highly subsidized in a Public health facility.

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References

  1. Verma IC. Burden of genetic disorders in India. Indian J Pediatr. 2000;67:893–8.

    Article  PubMed  CAS  Google Scholar 

  2. McCandless SE, Brunger JW, Cassidy SB. The burden of genetic disease on inpatient care in a children’s hospital. Am J Hum Genet. 2004;74:121–7.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  3. Centers for disease control and prevention. Hospital stays, hospital charges, and in-hospital deaths among infants with selected birth defects – United States, 2003. MMWR Morb Mortal Wkly Rep. 2007;56:25–9.

  4. Chen Y, Qian X, Zhang J, Li J, Chu A, Schweitzer SO. Preliminary study into the economic burden of Down syndrome in China. Birth Defects Res A Clin Mol Teratol. 2008;82:25–33.

    Article  PubMed  CAS  Google Scholar 

  5. Waitzman NJ, Romano PS, Scheffler RM. Estimates of the economic costs of birth defects. Inquiry. 1994;31:188–205.

    PubMed  CAS  Google Scholar 

  6. Russo CA, Elixhauser A. Hospitalizations for Birth Defects, 2004. HCUP Statistical Brief #24. January 2007. U.S. Agency for Healthcare Research and Quality, Rockville, MD. http://www.hcup-us.ahrq.gov/reports/statbriefs/sb24.pdf.

  7. Suresh S, Thangavel G, Sujatha J, Indrani S. Methodological issues in setting up a surveillance system for birth defects in India. Natl Med J India. 2005;18:259–62.

    PubMed  Google Scholar 

  8. Bale JR, Stoll BJ, Lucas AO (Eds). Reducing birth defects: Meeting the Challenge in the developing countries, 2003 National Academies Press, Washington DC Retrieved from http://books.nap.edu/openbook.php?isbn=0309086086.

  9. Colvin L, Bower C. A retrospective population-based study of childhood hospital admissions with record linkage to a birth defects registry. BMC Pediatr. 2009;9:32. doi:10.1186/1471-2431-9-32.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Kar A. Preventing birth defects in India. Econ Polit Weekly. 2011;XLVI:21–2.

    Google Scholar 

  11. Controlling Birth Defects: Reducing the Hidden Toll of Dying and Disabled Children in Low-Income Countries available at http://www.dcp2.org/file/230/dcpp-twpcongenitaldefects_web.pdf. Accessed 19 July 2013.

  12. Lahariya C, Paul VK. Burden, differentials, and causes of child deaths in India. Indian J Pediatr. 2010;77:1312–21.

    Article  PubMed  Google Scholar 

  13. Millennium development goals India country report 2011. Central Statistical Organization, Ministry of Statistics and Programme Implementation, Government of India, available at www.mospi.nic.in/. Accessed 19 July 2013.

  14. NIMS, ICMR, UNICEF, 2012, Infant and child mortality in India: Levels, trends and determinants, National Institute of Medical Statistics (NIMS), Indian Council of Medical Research (ICMR), and UNICEF India Country office, New Delhi, available at www.unicef.org/india/FactsheetExperts.pdf. Accessed 19 July 2013.

  15. Phadke SR. Malformation syndromes in India. In: Kumar D, ed. Genomics and health in the developing world. New York: Oxford University Press; 2012. pp. 1055–66.

  16. World health organization: global health expenditure database, available at http://apps.who.int/nha/database/DataExplorer.aspx?ws=0&d=1. Accessed on 19 August 2013.

  17. Waitzman NJ, Romano PS. Reduced costs of congenital anomalies from fetal ultrasound: are they sufficient to justify routine screening in the United States? Ann N Y Acad Sci. 1998;847:141–53.

    Article  PubMed  CAS  Google Scholar 

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Contributions

MM: Conceptualized the study, approved the protocol, analyzed the data and drafted the manuscript; VP: Recorded and analyzed the data and performed literature search. MM will act as guarantor for this paper.

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Correspondence to Mamta Muranjan.

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Muranjan, M., Vijayalakshmi, P. The Unforeseen Toll of Birth Defects and their Economic Burden at a Tertiary Care Public Institute in Mumbai. Indian J Pediatr 81, 1005–1009 (2014). https://doi.org/10.1007/s12098-014-1363-1

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  • DOI: https://doi.org/10.1007/s12098-014-1363-1

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