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Pulmonary Alveolar Proteinosis Secondary to Pneumocystis jiroveci Infection in an Infant with Common Variable Immunodeficiency

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Abstract

The authors report an infant with common variable immunodeficiency (CVID) with Pneumocystis pneumonia who developed secondary pulmonary alveolar proteinosis (PAP). This is the youngest infant reported to develop PAP secondary to Pneumocystis infection in an immunocompromised state. He was effectively managed with anti-microbials, frequent lung toilet, optimized mechanical ventilation, and supportive care.

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Fig. 1

Abbreviations

PAP:

Pulmonary alveolar proteinosis

MSG:

Major surface glycoprotein

GM-CSF:

Granulocyte-macrophage colony-stimulating factor

IVIg:

Intravenous immunoglobulin

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Authors and Affiliations

  1. Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India

    Dinesh Raj, Tsultem Doma Bhutia, Sushil Kumar Kabra & Rakesh Lodha

  2. Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India

    Sandeep Mathur

Authors
  1. Dinesh Raj
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  2. Tsultem Doma Bhutia
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  3. Sandeep Mathur
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  4. Sushil Kumar Kabra
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  5. Rakesh Lodha
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Corresponding author

Correspondence to Rakesh Lodha.

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Raj, D., Bhutia, T.D., Mathur, S. et al. Pulmonary Alveolar Proteinosis Secondary to Pneumocystis jiroveci Infection in an Infant with Common Variable Immunodeficiency. Indian J Pediatr 81, 929–931 (2014). https://doi.org/10.1007/s12098-013-1027-6

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  • DOI: https://doi.org/10.1007/s12098-013-1027-6

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