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Recurrent Femur Neck Fracture and Response to Bisphosphonates in Polyostotic Fibrous Dysplasia

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Abstract

Fibrous dysplasia is an uncommon metabolic bone disease. Medical management is often not rewarding. Index patient, a 15-year-old girl with history of recurrent fractures on trivial trauma was treated with pamidronate. She showed good outcome with symptomatic improvement and no new fractures over 3 year duration of follow up.

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References

  1. Biermann JS. Common benign lesions of bone in children and adolescents. J Pediatr Orthop. 2002;22:268–73.

    Article  PubMed  Google Scholar 

  2. Dimeglio LA. Bisphosphonates therapy for fibrous dysplasia. Pediatr Endocrinol Rev. 2007;4:440–5.

    PubMed  Google Scholar 

  3. Khadilkar VV, Khadilkar AV, Maskati GB. Oral bisphosphonates in polyostotic fibrous dysplasia. Indian Pediatr. 2003;40:894–6.

    PubMed  CAS  Google Scholar 

  4. Bhat MH, Bhadada S, Dutta P, Bhansali A, Mittal BR. Hyperthyroidism with fibrous dysplasia: an unusual presentation of McCune-Albright syndrome. Exp Clin Endocrinol Diabetes. 2007;115:331–3.

    Article  PubMed  CAS  Google Scholar 

  5. Riminucci M, Fisher LW, Shenker A, Spiegel AM, Bianco P, Gehron Robey P. Fibrous dysplasia of bone in McCune Albright Syndrome: abnormalities in bone formation. Am J Pathol. 1997;151:1587–600.

    PubMed  CAS  Google Scholar 

  6. Bhansali A, Sharma BS, Sreenivasulu P, Singh P, Vashisth R, Dash RJ. Acromegaly with fibrous dysplasia: McCune–Albright Syndrome. Clinical studies in 3 cases and brief review of literature. Endocr J. 2003;50:793–9.

    Article  PubMed  Google Scholar 

  7. Bhadada S, Bhansali A, Unnikrishnan AG, et al. Does Paget’s disease exist in India? J Assoc Physicians India. 2006;54:530–4.

    PubMed  CAS  Google Scholar 

  8. Bhadada SK, Bhansali A, Santosh R, Dutta P, Upreti V. Osteogenesis imperfecta: a series of 20 patients. J Assoc Physicians India. 2009;57:33–6.

    PubMed  CAS  Google Scholar 

  9. Lustig LR, Holliday MJ, Mc Carthy EF, Nager GT. Fibrous dysplasia involving the skull box and temporal bone. Arch Otolaryngol Head Neck Surg. 2001;127:1235–47.

    Google Scholar 

  10. Bhadada S, Sharma DC, Gupta LK, Gupta A, Gupta R. Fibrous dysplasia. J Indian Med Assoc. 1998;96:100.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Endocrinology, PGIMER, Chandigarh, 160012, India

    Ashu Rastogi, Sanjay Kumar Bhadada & Anil Bhansali

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  1. Ashu Rastogi
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  2. Sanjay Kumar Bhadada
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  3. Anil Bhansali
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Corresponding author

Correspondence to Sanjay Kumar Bhadada.

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Rastogi, A., Bhadada, S.K. & Bhansali, A. Recurrent Femur Neck Fracture and Response to Bisphosphonates in Polyostotic Fibrous Dysplasia. Indian J Pediatr 79, 667–669 (2012). https://doi.org/10.1007/s12098-011-0521-y

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  • DOI: https://doi.org/10.1007/s12098-011-0521-y

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