Abstract
Neonatal lupus erythematosus (NLE), in most cases, presents with cardiac and dermatological manifestation due to transferred IgG auto antibodies (anti Ro/SSA and anti La/SSB) from the mother. Some unusual associations with myelopathy, vasculopathy, transient myasthenia gravis, congenital nephrotic syndrome, chondrodysplasia punctata etc. are also reported. Here, the authors present a case of NLE with isolated left sided pectoralis major muscle atrophy, which has not been reported earlier.
References
Lela AL. Neonatal lupus erythematosus: clinical findings and pathogenesis. J Invest Dermatol. 2004;9:52–6.
Boh EE. Neonatal lupus erythematosus. Clin Dermatol. 2004;22:125–8.
Kaye EM, Butler IJ, Conley S. Myelopathy in neonatal and infantile lupus erythematosus. J Neurol Neurosurg Psychiatry. 1987;50:923–36.
Rider LG, Sherry DD, Glass ST. Neonatal lupus erythematosus simulating transient myasthenia gravis at presentation. J Pediatr. 1991;118:417–19.
Austin-Ward E, Castillo S, Cuchacovich M, et al. Neonatal lupus syndrome: a case with chondrodysplasia punctata and other unusual manifestations. J Med Genet. 1998;35:695–97.
Westenend PJ. Congenital nephrotic syndrome in neonatal lupus syndrome. J Pediatr. 1995;126:851.
Jarenon M, Martinez AL, Mayoralas FMD, Latova TM, Cabello A. Cap myopathy: a case report. Rev Neurol. 2007;45:669–71.
Deng JS, Bair LWJ, Shen-Schwarz, et al. Localization of Ro(SSA) antigen in the cardiac conduction system. Artritis Rheum. 1987;30:1232–38.
Contributions
RM, MN, SS and KM, were involved in the diagnosis and management of the patients. RM and MN searched the literature. RM and MN drafted the manuscript. KM did the critical review. All the authors approved the final version. RM and SS shall act as the guarantor.
Conflict of Interest
None.
Role of Funding Source
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Mondal, R., Nandi, M., Sarkar, S. et al. Neonatal Lupus Erythematosus Associated with Unilateral Pectoralis Major Atrophy. Indian J Pediatr 78, 1415–1416 (2011). https://doi.org/10.1007/s12098-011-0410-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12098-011-0410-4