Abstract
Objective
To determine the pre-campaign level of measles seropositivity and to evaluate the effect of a mass measles vaccination campaign on measles seroposivity among primary school children in Denizli, Turkey.
Methods
The study was completed in two socioeconomically different areas of Denizli, Turkey, with a sample size of 520 students. One primary school from each area and one classroom from each grade were randomly included in the sample. Before and 2-months after the measles mass vaccinations, blood samples were collected from the students and measles specific IgGs were studied.
Results
The pre-campaign overall seropositivity was 74.7%. Post-campaign overall seropositivity increased to 96.5%. Pre-campaign seropositivity among 8-graders was significantly lower than that in other grades (57.5%, p<0.001) and the difference was explained by the number of vaccinations 8-graders received. Except for the number of vaccination doses, other factors did not have any effect on seropositivity.
Conclusions
The mass measles vaccination programs have a potential to control measles for developing countries. In addition, more than one dose of measles vaccination is required for developing countries.
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References
Korukolu G. Elimination of measles in Turkey (Turkish). Monthly Epidemiol Bull 2003; 2: 65–67.
Köhler KA, Suleiman AJ, Robertson SE et al, Immuno-genicity of measles and rubella vaccines in Oman: a prospective clinical trial. J Infect Dia 2003; 187: S177–S185.
Kertesz DA, Toure K, Berthe A, Konate Y, Bougoudogo F. Evaluation of urban measles mass campaigns for children aged 9–59 months in Mali. J Infect Dis 2003; 187: S69–S73.
Nanyunja M, Lewis RF, Makumbi I et al. Impact of mass measles campaigns among children less than 5 years old in Uganda. J Infect Dis 2003; 187: S63–S68.
Lee MS, Nokes DJ, Wu YC, Huang YH, Lu CR Measles IgG seroprevalence prior to mass vaccination in Taiwan. Int J Infect Dis 2002; 6: 42–47.
Kuroiwa C, Xayyavong P, Vongpra Jianh P, Khampa-pongpane B, Yamanaka M, Nakumuro S. Diffucults in measles eliminations: Prevalance of measles antibodies before and after mass vaccinations campaign in Laos. Vaccine 2003; 21:479–484.
Pistol A, Hennessey K, Pitigoi D et al. Progress toward measles elimination in Romania after a mass vaccination campaign and implementation of enhanced measles surveillance. J Infect Dis 2003; 187: S217–S222.
Health Directory of Denizli province, Annual Health Statistics Yearbook. 2002.
Health Directory of Denizli province, Annual Health Statistics Yearbook. 2003.
Oktem F, Ozel A, Ozerol IH, Kaptanoglu B, Erkul I. City to investigation of measles antibodies in children vaccinated in the city of Konya (Turkish). SU Med Faculty J 1994; 10: 187–194.
Hamzaoglu O, Dikici H, Koseoglu V, Esin N, Basustaoglu A. Seroprevalence of measles in vaccined children ages 2–14 admitted to a medical school hospital outpatient clinic (Turkish). Turk J Hyg and Experiment Biol 1995; 52: 19–24.
Meral C, Karademir F, Bahar A, Emekdas GI, Kocabeyoglu M. The effectiveness of second dose of MMR vaccine at four to six year (Turkish). J Child Health and Dis 2001; 44: 207–212.
Egemen A, Aksit S, Ozacar T et al. Measles seroprevalence in Izmir with special emphasis on measles vaccination policy for Turkey. Pediatr Int 2001; 43: 379–384.
Ozkan S, Aksakal N, Baykan Z, Cirak M, Aycan S. Evaluation of immunity against measles in primary school children in Golbasi Baldudak Primary School (Turkish). T Clin J Pediatr 2001; 10: 202–208.
Ceyhan M, Erdem G. Measles-rubella-mumbs vaccines (Turkish). Katki Pediatr J 1998; 19: 172–194.
Lee MS, Chien LJ, Yueh YY, Lu CF. Measles seroepidemiology and decay rate of vaccine-induced measles IgG titers in Taiwan, 1995–1997. Vaccine 2001; 19: 4644–4651.
Ozkan S, Aycan S, Aycan Z, Beyazova U. Assesment of immunity against measles after a single dose at ninth month and two doses of measles vaccines for the ninth-fifteenth month among children under 5 years of age (Turkish). VI National Public Health Days, Abstract Book 1999; 47.
Turkish Health Ministry, General Directorate of Primary Health Care, Circular No. 137, dated 10/02/1998.
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Bozkurt, A.I., Bostanci, M., Cevahir, N. et al. Evaluation of a mass measles vaccination campaign among school children aged 7–14 years old in Denizli, Turkey. Indian J Pediatr 77, 879–883 (2010). https://doi.org/10.1007/s12098-010-0124-z
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DOI: https://doi.org/10.1007/s12098-010-0124-z