Abstract
Galactosemia is one of the rare inborn errors of metabolism, which if detected early can be treated effectively. Galactosemic infants have a significant increased risk of developing sepsis. E. coli sepsis is a known entity, and also an important cause of early mortality in these children. But fungal sepsis in these patients is rarely reported. Here is a case of 45 day-old child who presented with fungal sepsis, which on investigation turned out to be galactosemia.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Barr PH. Association of Escherichia coli sepsis and galactosemia in neonates. J Am Board Fam Pract 1992; 5: 89–91.
Levy HL, Sepe SJ, Shih VE, Vawter GF, Klein JO. Sepsis due to Escherichia coli in neonates with galactosemia. N Engl J Med 1977; 297: 823–825.
Shurin SB. Escherichia coli septicemia in neonates with galactosemia. N Engl J Med 1977; 297: 1403–1404.
Kobayashi RH, Kettelhut BV, Kobayashi AL. Galactose inhibition of neonatal neutrophil function. Pediatr Infect Dis 1983; 2: 442–445.
Waggoner DD, Buist NR, Donnell GN. Long-term prognosis in galactosaemia: results of a survey of 350 cases. J Inherit Metab Dis 1990; 13: 802–818.
Ng WG, Xu YK, Wong LJ, Kaufman FR, Buist NR, Donnell GN. Two adult galactosaemia females with normal ovarian function and identical GALT mutations. J Inherit Metab Dis 2003; 26: 75–79.
Bosch AM. Classical galactosaemia revisited. J Inherit Metab Dis 2006; 29: 516–525.
Lambert C, Boneh A. The impact of galactosaemia on quality of life-a pilot study. J Inherit Metab Dis 2004; 27: 601–608.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Verma, S., Bharti, B. & Inusha, P. Association of fungal sepsis and galactosemia. Indian J Pediatr 77, 695–696 (2010). https://doi.org/10.1007/s12098-010-0082-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12098-010-0082-5