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Apparent hypocortisolism in an infant with prolonged hyperinsulinism

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Abstract

We report a case of transient hyperinsulinism with hypocortisolemia in a preterm small for date neonate with recurrent hypoglycemia and perinatal stress. Investigation revealed increased Insulin level with subnormal cortisol level even during hypoglycemia. Hypoglycemia resolved by its own by 22nd day of life with normal insulin and cortisol level thereafter.

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References

  1. Aynsley-Green A, Soltesz G. Hypoglycaemia in infancy and childhood. In: Chambers T, Aynsley-Green A, eds. Current reviews in paediatrics. Edingurgh: Churchhill-Livingstone, 1985”.

    Google Scholar 

  2. Palladino AA, Bennett MJ, Stanley CA. Hyperinsulinism in infancy and childhood; when an insulin level is not always enough. Clin Chem 2008; 54: 256–263.

    Article  CAS  PubMed  Google Scholar 

  3. Collins JE, Leonard JV, Teale D et al. Hyperinsulinaemic hypoglycaemia in small for dates babies. Arch Dis Child 1990; 65: 1118–1120.

    Article  CAS  PubMed  Google Scholar 

  4. Jain A, Aggarwal R, Jeevasanker R, Agarwal R, Deorari A, Paul VK. Hypoglycemia in the Newborn. Indian J Pediatr 2008; 75: 63–67

    Article  PubMed  Google Scholar 

  5. Hussain K, Aynsley-Green A. Hyperinsulinaemic hypoglycaemia in preterm neonates. Arch Dis Child Fetal Neonatal Ed 2004;89:F65–F67

    Article  CAS  PubMed  Google Scholar 

  6. Collins JE, Leonard JV. Hyperinsulinism in asphyxiated and small for dates infants with hypoglycaemia. Lancet 1984; ii: 311–313

    Article  Google Scholar 

  7. Sperling MA: Hypoglycemia. Nelson Textbook of Pediatrics. Saunders publication 18th ed. Vol 1, 655–668.

  8. Crofton PM, Midgley PC. Cortisol and growth hormone responses to spontaneous hypoglycaemia in infants and children. Arch Dis Child 2004; 89: 472–478.

    Article  CAS  PubMed  Google Scholar 

  9. Hawdon J M, Weddell A, Aynsley-Green A, Ward Platt M P. Hormonal and metabolic response to hypoglycaemia in small for gestational age infants. Arch Dis Child 1993; 68: 269–273

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatrics and Neonatology, Dr. Ram Manohar Lohia Hospital New Delhi, New Delhi, India

    Vijay Gupta & V. K. Gupta

  2. C/o Chaudhary Traders, Dal Bazaar, Lashkar Gwalior, M.P., India

    Vijay Gupta

Authors
  1. Vijay Gupta
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  2. V. K. Gupta
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Correspondence to Vijay Gupta.

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Gupta, V., Gupta, V.K. Apparent hypocortisolism in an infant with prolonged hyperinsulinism. Indian J Pediatr 77, 321–322 (2010). https://doi.org/10.1007/s12098-009-0305-9

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  • DOI: https://doi.org/10.1007/s12098-009-0305-9

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