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Clinical significance of multi-slice spiral CT, MRI combined with gastric contrast-enhanced ultrasonography in the diagnosis of T staging of gastric cancer

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Abstract

Purpose

To explore the application value of multi-slice spiral CT (MSCT), magnetic resonance imaging (MRI) combined with gastric contrast-enhanced ultrasonography in the diagnosis of T staging of gastric cancer.

Methods

The subjects of study were 109 gastric cancer patients with T stages admitted to our hospital for diagnosis and treatment from December 2016 to December 2018. All the patients were examined with MSCT, MRI and gastric contrast-enhanced ultrasonography before operation to observe corresponding imaging results. T staging of gastric cancer patients was conducted according to the examination results, which was then compared with postoperative pathological staging. It was performed to analyze the accuracy of the three diagnostic methods and combined diagnosis of gastric cancer T staging.

Results

The sensitivity of MSCT in the diagnosis of T staging of gastric cancer was 60.00%, 67.74%, 72.22%, 76.47%, the specificity was 95.24%, 88.46%, 86.30%, 94.56% and the diagnostic coincidence rate was 87.16%, 82.57%, 81.65%, 91.74%; the sensitivity of MRI in the diagnosis of T staging of gastric cancer was 68.00%, 70.97%, 77.78%, 76.47%, the specificity was 92.86%, 88.46%, 91.78%, 95.65%, and the diagnostic coincidence rate was 87.16%, 83.49%, 87.16%, 92.66%; the sensitivity of gastric contrast-enhanced ultrasonography in the diagnosis of T staging of gastric cancer was 80.00%, 83.87%, 86.11%, 82.35%, the specificity was 97.62%, 92.31%, 91.78%, 97.83%, and the diagnostic coincidence rate was 93.58%, 89.91%, 89.91%, 95.41%; the sensitivity of combined MSCT, MRI and gastric contrast-enhanced ultrasonography in the diagnosis of T staging of gastric cancer was 88.00%, 93.55%, 97.22%, 94.12%; the specificity was 100%, 97.44%, 95.89%, 98.91%; and the diagnostic coincidence rate was 97.25%, 96.33%, 96.33%, 98.17%, respectively. Statistical analysis revealed that the sensitivity, specificity and diagnostic coincidence rate of combined detection of the three methods were significantly higher than those of single detection (P < 0.05).

Conclusion

Combined use of MSCT, MRI and gastric contrast-enhanced ultrasonography can significantly improve the diagnostic sensitivity, specificity and diagnostic coincidence rate of T staging of gastric cancer. It may provide a certain reference value for guiding the selection of clinical therapeutic approaches and evaluation of curative effect.

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Authors and Affiliations

  1. Department of Imaging, Yantaishan Hospital, Yantai, 264000, China

    Q. -Z. Gai

  2. Image Center, Dongchangfu People’s Hospital, Liaocheng People’s Hospital, Liaocheng, 252000, China

    X. -L. Li

  3. ICU, Affiliated Qingdao Central Hospital, Qingdao University, Qingdao, 266000, China

    N. Li

  4. Department of Neurosurgery, Zhangqiu District People’s Hospital, Jinan, 250200, China

    L. Li

  5. Department of Ultrasound, Zhangqiu District People’s Hospital, Jinan, 250200, China

    Z. Meng

  6. Department of Ultrasound, East Hospital, Qingdao Municipal Hospital, No .5 Donghai Middle Road, Qingdao, 266071, China

    A. -F. Chen

Authors
  1. Q. -Z. Gai
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  2. X. -L. Li
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  3. N. Li
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  4. L. Li
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  5. Z. Meng
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  6. A. -F. Chen
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Contributions

QG and XL conceived the study and drafted the manuscript. NL and LL contributed to the acquisition, analysis, or interpretation of data for the work. ZM and AC were responsible for MSCT examination, MRI examination and pathological examination. All authors finally approved the manuscript version to be published.

Corresponding author

Correspondence to A. -F. Chen.

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The authors declare that they have no conflict of interest.

Ethical approval

The study was approved by Ethical Committee of Yantaishan Hospital and conducted in accordance with the ethical standards.

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Subjects signed the informed consent.

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Gai, Q.Z., Li, X.L., Li, N. et al. Clinical significance of multi-slice spiral CT, MRI combined with gastric contrast-enhanced ultrasonography in the diagnosis of T staging of gastric cancer. Clin Transl Oncol 23, 2036–2045 (2021). https://doi.org/10.1007/s12094-021-02606-9

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  • DOI: https://doi.org/10.1007/s12094-021-02606-9

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