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Clinical and Translational Oncology

, Volume 15, Issue 3, pp 243–247 | Cite as

A high body mass index is not a worse prognostic factor for endometrial carcinoma in a predominantly obese population

  • Leonardo Saúl Lino-SilvaEmail author
  • David Cantú de León
  • Rosa Angélica Salcedo-Hernández
  • Claudia Cavazos-Saman
  • María Delia Pérez-Montiel
Brief Research Article

Abstract

Aim

We investigate if body mass index (BMI, kg × m2) is related to clinical–pathological characteristics in primary tumor and disease outcome in endometrial cancer.

Background

Endometrial cancer incidence is increasing in industrialized countries. High BMI is associated with worse prognosis for many diseases.

Introduction

Endometrial carcinoma is the most common gynecological malignancy in industrialized countries and the incidence has been increasing over the last few decades associated with obesity, however, it is not clear if a high BMI is associated with poor prognosis.

Patients and methods

In total, 147 women primarily treated for endometrial carcinoma at the Instituto Nacional de Cancerología during 2000–2005 were studied. Body mass index was available for all patients and related to comprehensive clinical and histopathological data.

Results

High BMI was related to endometrioid histology and low/intermediate grade, and overweight/obese women had the same survival as the normal/underweight women. In survival analysis adjusting for age, histological subtype and grade, BMI showed no independent prognostic impact.

Conclusion

High BMI was significantly associated with markers of non-aggressive disease and women with high BMI had the same survival time in univariate analysis.

Keywords

Endometrial carcinoma Endometrioid adenocarcinoma Body mass index Obesity Female cancer 

Notes

Conflict of interest

We have no conflict of interest.

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Copyright information

© Federación de Sociedades Españolas de Oncología (FESEO) 2012

Authors and Affiliations

  • Leonardo Saúl Lino-Silva
    • 1
    Email author
  • David Cantú de León
    • 2
  • Rosa Angélica Salcedo-Hernández
    • 2
  • Claudia Cavazos-Saman
    • 1
  • María Delia Pérez-Montiel
    • 1
  1. 1.Anatomic PathologyInstituto Nacional de Cancerología de MéxicoMexico CityMexico
  2. 2.Ginecologycal OncologyInstituto Nacional de Cancerología de MéxicoMexico CityMexico

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