Abstract
Neuroendocrine small cell carcinoma of the uterine cervix (SCC) is a rare disease that mixes clinical and biological characteristics of both cervical neoplasms and neuroendocrine small cell cancer. The prognosis is poor and the optimal treatment has not yet been clarified. Multimodality treatment, with surgery and concurrent chemoradiation has recently been shown to improve local control and survival rates.
Similar content being viewed by others
References
Crowder S, Tuller E (2007) Small cell carcinoma of the female genital tract. Semin Oncol 34:57–63
Trinh X-B, Bogers JJ, Van Marck EA et al (2004) Treatment policy of neuroendocrine small cell cancer of the cervix. Eur J Gynaecol Oncol 25:40–44
Delaloge S, Pautier P, Kerbrat P et al (2000) Neuroendocrine small cell carcinoma of the uterine cervix: What disease? What treatment? Report of ten cases and a review of the literature. Clin Oncol 12:357–362
Bifulco G, Mandato VD, Giampaolino P et al (2009) Small cell neuroendocrine cervical carcinoma with 1-year follow-up: case report and review. Anticancer Res 29:477–484
Chan JK, Loizzi V, Burger RA et al (2003) Prognostic factors in neuroendocrine small cell cervical carcinoma: a multivariate analysis. Cancer 97: 568–574
Abeler VM, Holm R, Nesland JM, Kjorstad KE (1994) Small cell carcinoma of the cervix. A clinicopatologic study of 26 patients. Cancer 73: 672–677
Wentz WB, Reagan JW (1959) Survival in cervical cancer with respect to cell type. Cancer 12:384
Weed JC, Graff AT, Shoup B et al (2003) Small cell undifferentiated (neuroendocrine) carcinoma of the uterine cervix. J Am Coll Surg 197:44–51
Hoskins PJ, Swenerton KD, PiKe JA et al (2003) Small cell carcinoma of the cervix: Fourteen years of experience at a single institution using a combined modality regimen of involved-field irradiation and platinum-based combination chemotherapy. J Clin Oncol 21:3495–3501
Morris M, Gershenson DM, Eifel P et al (1992) Treatment of small cell carcinoma of the cervix with cisplatin, doxorubicin and etoposide. Gynecol Oncol 47:62–65
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Reig Castillejo, A., Membrive Conejo, I., Foro Arnalot, P. et al. Neuroendocrine small cell carcinoma of the uterine cervix. Clin Transl Oncol 12, 512–513 (2010). https://doi.org/10.1007/s12094-010-0546-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12094-010-0546-0