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Spanish radiobiological pattern of care in lung cancer: a GOECP/SEOR study

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Abstract

Introduction

A survey regarding radiobiological questions in the treatment of lung cancer (LC) was done to study the clinical aspects of radiotherapy in Spain, in order to standardise treatment decisions.

Methods and materials

From November 2007 to March 2008, a survey was performed among radiation oncologists in Spain specialising in LC treatment via e-mail, which included questions regarding different radiobiological aspects of radiotherapy LC treatment. The extent of the resulting material made it necessary to divide it into two parts; the first is presented in this article. The second, which includes items about α/β-NTCP/TCP values and reirradiation criteria, will be reported elsewhere.

Results

Thirty-one radiation therapists from 29 radiation oncology departments answered the survey. 77.4–93.5% of responders used the basic formula from the linear-quadratic model and/or computer software for radiobiological calculations; 100% used lung (mostly V20, median <30%) and spinal cord constraints (mostly a median of physical maximum dose <45.5 Gy); and 90.3% used heart and oesophagus constraints (very heterogeneous parameters in both organs).

Conclusions

Radiobiological considerations are clearly present in the planning process of radiotherapy of LC in Spain, with a high coincidence with the literature regarding lung and spinal cord constraints. The heterogeneity shown for oesophagus and heart results demonstrates the need for continuing investigation into the standardisation of clinical, dosimetric and radiobiologic aspects of the treatment of this cancer.

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Authors and Affiliations

  1. Department of Radiation Oncology, Instituto Madrileño de Oncología (IMO Group) Unidad Regional de Guadalajara Pol. Industrial El Balconcillo, C/ Méjico-esq. Antonio Machado, ES-19004, Guadalajara, Spain

    José A. González

  2. Department of Radiation Oncology, Hospital Universitario Infanta Cristina, Badajoz, Spain

    José A. González

  3. Department of Radiation Oncology, Fundación Instituto Valenciano de Oncología (IVO), Valencia, Spain

    Marisa Chust

  4. Department of Radiation Oncology, Hospital Regional Universitario Carlos Haya, Málaga, Spain

    Raquel Delgado

  5. Department of Radiation Oncology, Hospital Clínico Universitario Santiago de Compostela Santiago de Compostela, La Coruña, Spain

    Antonio Gómez

  6. Department of Radiation Oncology Hospitales del Mar y de la Esperanza, Universidad Pompeu Fabra, Barcelona, Spain

    Nuria Rodríguez

  7. Department of Radiation Oncology, Hospital Universitario La Paz, Madrid, Spain

    María J. Ruiz

  8. Department of Radiation Oncology, Hospital Clinic, Barcelona, Spain

    Francesc Casas

Authors
  1. José A. González
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  2. Marisa Chust
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  3. Raquel Delgado
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  4. Antonio Gómez
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  5. Nuria Rodríguez
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  6. María J. Ruiz
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  7. Francesc Casas
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on behalf of GOECP/SEOR (Oncological Group for Study of Lung Cancer/Spanish Society of Radiation Oncology)

Corresponding author

Correspondence to José A. González.

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González, J.A., Chust, M., Delgado, R. et al. Spanish radiobiological pattern of care in lung cancer: a GOECP/SEOR study. Clin Transl Oncol 12, 292–298 (2010). https://doi.org/10.1007/s12094-010-0506-8

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  • DOI: https://doi.org/10.1007/s12094-010-0506-8

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