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Clinical and Translational Oncology

, Volume 12, Issue 3, pp 231–233 | Cite as

Primary intracranial malignant peripheral nerve sheath tumour responding to chemotherapy

  • Francisco ZambranaEmail author
  • David Vicente
  • Teresa García-Manrique
  • Sofía Pereira
  • Jesús Sáinz De Zaitigui
  • Luis De La Cruz Merino
Case Reports

Abstract

Malignant peripheral nerve sheath tumours (MPNST) are a rare variety of soft tissue sarcomas (STS) arising from major peripheral nerve branches and typically located in the lower extremity, chest wall or the retroperitoneum. It is a biologically aggressive neoplasm for which the treatment of choice is surgery, but usually requires a multimodality approach, having been generally labelled as chemoresistant. We present a case of MPNST located intracranially with a good response to chemotherapy.

Keywords

Malignant peripheral nerve sheath tumour Intracranial Soft tissue sarcoma Chemotherapy 

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Copyright information

© Feseo 2010

Authors and Affiliations

  • Francisco Zambrana
    • 1
    Email author
  • David Vicente
    • 2
  • Teresa García-Manrique
    • 2
  • Sofía Pereira
    • 3
  • Jesús Sáinz De Zaitigui
    • 4
  • Luis De La Cruz Merino
    • 2
  1. 1.Department of Medical OncologyHospital Infanta Sofía Paseo de EuropaMadridSpain
  2. 2.Department of Medical OncologyHospital Universitario Virgen MacarenaSevillaSpain
  3. 3.Department of PathologyHospital Universitario Virgen MacarenaSevillaSpain
  4. 4.Department of RadiologyHospital Universitario Virgen MacarenaSevillaSpain

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