Clinical and Translational Oncology

, Volume 10, Issue 9, pp 597–598 | Cite as

An autopsy case of acute pulmonary toxicity related to irinotecan

  • Ana Ruiz-CasadoEmail author
  • Víctor Castellano
  • Fernando Moreno


Irinotecan Camptothecin Pulmonary Toxicity Interstitial Pneumonitis Diffuse Alveolar Damage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Terrabuio AA, Parra ER, Farhat C, Capelozzi VL (2007) Autopsy-proven causes of death in lungs of patients immunocompromised by secondary interstitial pneumonia. Clinics 62:69–76CrossRefGoogle Scholar
  2. 2.
    Rossi SE, Erasmus JJ, Page McAdams H et al (2000) Pulmonary drug toxicity: radiologic and pathologic manifestations. Radiographics 20: 1245–1259. ReviewPubMedGoogle Scholar
  3. 3.
    Dimopoulou I, Barnias A, Lyberopoulos P, Dimopoulos MA (2006) Pulmonary toxicity from novel antineoplastic agents. Ann Oncol 17: 372–379PubMedCrossRefGoogle Scholar
  4. 4.
    Fukuoka M, Niitani H, Suzuki A et al (1992) A phase II study of CPT-11 a new derivative of camptothecin, for previously untreated non-small cell lung cancer. J Clin Oncol 10:16–20PubMedGoogle Scholar
  5. 5.
    Masuda N, Fukuoka M, Kusunoki Y et al (1992) CPT 11: a new derivative of camptothecin for the treatment of refractory or relapsed small cell lung cancer. J Clin Oncol 10:1225–1229PubMedGoogle Scholar
  6. 6.
    Madarnas Y, Webster P, Shorter AM et al (2000) Irinotecan-associated pulmonary toxicity. Anti-cancer Drugs 11:709–713PubMedCrossRefGoogle Scholar
  7. 7.
    Michielin O, Udry E, Periard D et al (2004) Irinotecan-induced interstitial pneumonia. Lancet Oncol 5:322–324PubMedCrossRefGoogle Scholar

Copyright information

© Feseo 2008

Authors and Affiliations

  • Ana Ruiz-Casado
    • 1
    Email author
  • Víctor Castellano
    • 2
  • Fernando Moreno
    • 1
  1. 1.Department of Medical OncologyHospital Universitario de FuenlabradaFuenlabrada, MadridSpain
  2. 2.Department of PathologyHospital Universitario de FuenlabradaMadridSpain

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