Recurrence and survival in surgically treated endometrioid endometrial cancer

  • Alex SanjuánEmail author
  • Teresa Cobo
  • Georgia Escaramís
  • Angels Rovirosa
  • Jaume Ordi
  • Sonia García
  • Sandra Hernández
  • Xavier Caparrós
  • Aureli Torné
  • Sergio Martínez Román
  • Juan Antonio Lejárcegui
  • Jaume Pahisa
Research Articles



The objective of this study was to evaluate different surgical treatments and radiotherapy on patterns of recurrence and overall survival in patients with endometrioid-type endometrial cancer.

Materials and methods

The retrospective records of 162 patients with endometrioid endometrial cancer were collected. Patients were surgically treated from 1997 to 2002. Recurrence and survival were analyzed according to patient age, surgical procedure, lymphadenectomy, externalbeam irradiation, brachytherapy, surgical stage, myometrial invasion, and tumor grade. Standard statistical calculations were used.


Median age was 64 years. Median follow-up was 44 months. Overall, ten patients (5.6%) experienced recurrence and 14 (8.6%) died. With univariate analysis, statistical significance for survival was found for age older than 70 years, tumor grade, myometrial invasion, and stage. Multivariate analysis, however, found only age, stage, and grade to be significant. With univariate analysis, statistical significance for recurrence was found for tumor grade, stage, and external-beam radiotherapy as risk factors. Multivariate analysis found only radiotherapy and brachytherapy to be significant, but in an inverted sense, with brachytherapy having a protective effect.


Our results suggest that brachytherapy protects against recurrence and that neither a surgical approach nor a lymphadenectomy appear to affect recurrence or survival in patients with surgically treated endometrioid endometrial cancer.


Endometrial cancer Recurrence Brachytherapy Lymphadenectomy 


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Copyright information

© Feseo 2008

Authors and Affiliations

  • Alex Sanjuán
    • 1
    Email author
  • Teresa Cobo
    • 1
  • Georgia Escaramís
    • 4
  • Angels Rovirosa
    • 2
  • Jaume Ordi
    • 3
  • Sonia García
    • 1
  • Sandra Hernández
    • 1
  • Xavier Caparrós
    • 1
  • Aureli Torné
    • 1
  • Sergio Martínez Román
    • 1
  • Juan Antonio Lejárcegui
    • 1
  • Jaume Pahisa
    • 1
  1. 1.Department of Gynecology & Obstetrics Hospital Clínic i ProvincialUniversity of BarcelonaBarcelonaSpain
  2. 2.Department of Radiation Oncology Hospital Clínic i ProvincialUniversity of BarcelonaBarcelonaSpain
  3. 3.Department of Pathology Hospital Clínic i ProvincialUniversity of BarcelonaBarcelonaSpain
  4. 4.Department of Public HealthUniversity of BarcelonaBarcelonaSpain

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