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Clinical and Translational Oncology

, Volume 9, Issue 8, pp 537–539 | Cite as

Pathological femur fracture secondary to radiation therapy for soft tissue sarcoma

  • C. ConillEmail author
  • X. Tomás
  • A. Combalia-Aleu
  • A. Palacín
  • I. Planas
  • J. Maurel
Case Reports

Abstract

Bone fracture is a well known possible late complication of radiation treatment. Little has been written about fractures of long bones after irradiation. We present a case of femur bone necrosis secondary to postoperative radiation for a soft tissue sarcoma of the thigh 20 years earlier. Fixation of the diaphyseal fracture and radiological evolution are described.

Key words

Radiation therapy Late effects Surgery Soft tissue sarcoma Pathological fracture Osteoradionecrosis 

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References

  1. 1.
    Rosenberg SA, Tepper J, Glatstein E et al (1982) The treatment of soft tissue sarcomas of the extremities. Prospective randomized evaluations of (1) Limbsparing surgery plus radiation therapy compared with amputation; (2) The role of adjuvant chemotherapy. Ann Surg 196:305–315PubMedCrossRefGoogle Scholar
  2. 2.
    Yang JC, Chang AE, Baker AR et al (1998) Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity. J Clin Oncol 16:197–203PubMedGoogle Scholar
  3. 3.
    Peat BG, Bell RS, Davis A et al (1994) Wound healing complications after soft tissue sarcoma surgery. Plastic Reconstr Surg 93:980–987CrossRefGoogle Scholar
  4. 4.
    Kunisada T, Ngan SY, Powell G, Choong PFM (2002) Wound complications following pre-operative radiotherapy for soft tissue sarcoma. Eur J Surg Oncol 28:75–79PubMedCrossRefGoogle Scholar
  5. 5.
    Bell RS, O’sullivan B, Nguyen C et al (1991) Fractures following limb-salvage surgery and adjuvant irradiation for soft-tissue sarcoma. Clin Orthop 271:265–271PubMedGoogle Scholar
  6. 6.
    Lin PP, Schupak KD, Boland PJ et al (1998) Pathologic femoral fracture after periosteal excision and radiation for the treatment of soft tissue sarcoma. Cancer 82:2356–2365PubMedCrossRefGoogle Scholar
  7. 7.
    Scherk A, Conill C, Giralt J, Salvador L (1986) Post-irradiation osteosarcoma: a propos of a case. Med Clin (Barc) 87:649Google Scholar
  8. 8.
    Parker RG, Berry HC (1976) Late effects of therapeutic irradiation on the skeleton and bone marrow. Cancer 37:1162–1171PubMedCrossRefGoogle Scholar
  9. 9.
    Hong L, Alektiar KM, Hunt M et al (2004) Intensity-modulated radiotherapy for soft tissue sarcoma of the thigh. Int J Radiat Oncol Biol Phys 59:752–759PubMedCrossRefGoogle Scholar
  10. 10.
    van Duyn EB, Werker PM, van der Werken C (2001) Free vascularised fibula transplantation for treatment of a fractured femur after radiation therapy. Injury 32:82–86PubMedCrossRefGoogle Scholar

Copyright information

© Feseo 2007

Authors and Affiliations

  • C. Conill
    • 1
    Email author
  • X. Tomás
    • 2
  • A. Combalia-Aleu
    • 3
  • A. Palacín
    • 4
  • I. Planas
    • 1
  • J. Maurel
    • 5
  1. 1.Department of Radiation Oncology (ICMHO) Musculoskeletal Oncology Unit, Hospital ClinicInstitut d’Investigacions Biomédiques August Pi i Sunyer (IDIBAPS)BarcelonaSpain
  2. 2.Department of Radiology (CDIC). Musculoskeletal Oncology Unit. Hospital ClinicInstitut d’Investigacions Biomédiques August Pi i Sunyer (IDIBAPS)BarcelonaSpain
  3. 3.Department of Orthopedic Surgery (ICAL). Musculoskeletal Oncology Unit. Hospital ClinicInstitut d’Investigacions Biomédiques August Pi i Sunyer (IDIBAPS)BarcelonaSpain
  4. 4.Department of Pathology (CDB). Musculoskeletal Oncology Unit. Hospital ClinicInstitut d’Investigacions Biomédiques August Pi i Sunyer (IDIBAPS)BarcelonaSpain
  5. 5.Department of Medical Oncology (ICMHO). Musculoskeletal Oncology Unit. Hospital ClinicInstitut d’Investigacions Biomédiques August Pi i Sunyer (IDIBAPS)BarcelonaSpain

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