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Primary duodenal follicular lymphoma successfully treated with rituximab

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Abstract

Non-Hodgkin’s lymphoma (NHL) of the gastrointestinal (GI) tract is the most common extranodal lymphoma, accounting for approximately 40% of all extranodal NHLs. Initial treatment of duodenal lymphoma includes surgery, chemotherapy and radiotherapy, alone or in combination. Here, we present a case of stage I primary duodenal follicular lymphoma (FL) showing a complete response after rituximab therapy. Rituximab alone can be an effective alternative treatment for duodenal FL.

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References

  1. Koch P, del Valle F, Berdel WE et al (2001) Primary gastrointestinal non-Hodgkin’s lymphoma: I. Anatomic and histologic distribution, clinical features, and survival data of 371 patients registered in the German multicenter study GIT NHL 01/92. J Clin Oncol 19:3861–3873

    PubMed  CAS  Google Scholar 

  2. Gurney KA, Cartwright RA, Gilman EA (1999) Descriptive epidemiology of gastrointestinal non-Hodgkin’s lymphoma in a population-based registry. Br J Cancer 79:1929–1934

    Article  PubMed  CAS  Google Scholar 

  3. Amer MH, El-Akkad S (1994) Gastrointestinal lymphoma in adults: clinical features and management of 300 cases. Gastroenterology 106:846–858

    PubMed  CAS  Google Scholar 

  4. Damaj G, Verkarre V, Delmer A et al (2003) Primary follicular lymphoma of the gastrointestinal tract: a study of 25 cases and a literature review. Ann Oncol 14:623–629

    Article  PubMed  CAS  Google Scholar 

  5. Yoshino T, Miyake K, Ichimura K et al (2000) Increased incidence of follicular lymphoma in the duodenum. Am J Surg Pathol 24:688–693

    Article  PubMed  CAS  Google Scholar 

  6. Shia J, Teruya Feldstein J, Pan D et al (2002) Primary follicular lymphoma of the gastrointestinal tract: a clinical and pathologic study of 26 cases. Am J Surg Pathol 26:216–224

    Article  PubMed  Google Scholar 

  7. Harris NL, Jaffe ES, Diebold J et al (1999) World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting, Airlie House, Virginia, November 1997. J Clin Oncol 17:3835–3849

    PubMed  CAS  Google Scholar 

  8. Bende RJ, Smit LA, Bossenbroek JG et al (2003) Primary follicular lymphoma of the small intestine: alpha4beta7 expression and immunoglobulin configuration suggest an origin from local antigen-experienced B cells. Am J Pathol 162:105–113

    PubMed  CAS  Google Scholar 

  9. Misdraji J, Del Castillo CF, Ferry JA (1997) Follicle center lymphoma of the ampulla of Vater presenting with jaundice: report of a case. Am J Surg Pathol 21:484–488

    Article  PubMed  CAS  Google Scholar 

  10. Ahmed S, Singh A, Krauss J et al (2003) Successful treatment of refractory low grade duodenal lymphoma with rituximab, an anti-cd20 monoclonal antibody. Am J Clin Oncol 26:408–410

    Article  PubMed  Google Scholar 

  11. Zenda T, Masunaga T, Fuwa B et al (2005) Small follicular lymphoma arising near the ampulla of Vater. A distinct subtype of duodenal lymphoma? J Gastrointest Cancer 36:113–120

    Article  Google Scholar 

  12. Takamura M, Narisawa R, Maruyama Y et al (2006) A primary follicular lymphoma of the duo denum treated successfully with radiation therapy. Intern Med 45:309–311

    Article  PubMed  Google Scholar 

  13. Grillo-Lopez AJ, White CA, Varns C et al (1999) Overview of the clinical development of rituximab: first monoclonal antibody approved for the treatment of lymphoma. Semin Oncol 26[5 Suppl 14]:66–73

    PubMed  CAS  Google Scholar 

  14. Hiddemann W, Kneba M, Dreyling M et al (2005) Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves the outcome for patients with advanced-stage follicular lymphoma compared with therapy with CHOP alone: results of a prospective randomized study of the German Low-Grade Lymphoma Study Group. Blood 106:3725–3732

    Article  PubMed  CAS  Google Scholar 

  15. Coiffier B, Lepage E, Briere J et al (2002) CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med 346:235–242

    Article  PubMed  CAS  Google Scholar 

  16. Al-Salman J, Salib H, Boonswang P (2001) Successful treatment of gastrointestinal follicular lymphoma with rituxan and combination chemotherapy. Med Oncol 18:277–283

    Article  PubMed  CAS  Google Scholar 

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Correspondence to D. Aguiar-Bujanda.

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Aguiar-Bujanda, D., Quiñones-Morales, I., Camacho-Galán, R. et al. Primary duodenal follicular lymphoma successfully treated with rituximab. Clin Transl Oncol 9, 471–472 (2007). https://doi.org/10.1007/s12094-007-0088-2

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  • DOI: https://doi.org/10.1007/s12094-007-0088-2

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