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Testicular neoplasms. Evaluation of the experience during 25 years in a military hospital

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Abstract

Introduction

Testicular tumors are frequent in young adults, coinciding with incorporation to military service. The present study evaluates the tumor characteristics, time course and results obtained with the treatments used in our center for this type of neoplasms.

Material and methods

A retrospective longitudinal study was conducted in a cohort of 98 patients with an average age of 28.6 years, subjected to orchiectomy for testicular tumors in our center between 1979 and 2004. Data were collected relating to patient age, tumor characteristics, the outcome of treatment, and the course of the disease.

Results

The right testicle was affected in 61% (with significant differences versus the left side). The most common histological type corresponded to non-seminomatous germ cell tumors (NSGCTs) (65.3%), followed by pure seminomas (27.6%) and non-germinal cell tumors (NGCs) (7.1%). NSGCT was diagnosed at a significantly younger average age (23.2 years) than the other two tumor types. Stage I was the most frequent presentation (58%). Seminomas presented in stage I significantly more often (80%) than the others tumors. The data collected over the 25-year study period showed no significant variations in tumor characteristics. Thelog-rank test showed a significant difference in terms of patient survival according to the tumor cell line (p=0.000) and stage (p=0.000), except between stages I and II, where no significant differences were observed in terms of survival.

Conclusions

Non-seminomatous germ cell tumors (NSGCTs) are the most frequent testicular tumors in young adults. Most neoplasms are diagnosed in early stages, the prognosis being better in the case of seminomas and tumor stages I and II.

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Authors and Affiliations

  1. Service of Urology, Defense Central Hospital, C/Argentina, 4, 1-1, 28027, Madrid, Spain

    Ramón Diz-Rodríguez, Miguel Vírseda-Chamorro, Pedro Paños-Lozano, Ignacio Arance-Gil & Ana Moreno Posadas

  2. Service of Oncology, Defense Central Hospital, Madrid, Spain

    Antonio Colmenarejo Rubio

Authors
  1. Ramón Diz-Rodríguez
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  2. Miguel Vírseda-Chamorro
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  3. Pedro Paños-Lozano
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  4. Antonio Colmenarejo Rubio
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  5. Ignacio Arance-Gil
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  6. Ana Moreno Posadas
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Corresponding author

Correspondence to Miguel Vírseda-Chamorro.

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Diz-Rodríguez, R., Vírseda-Chamorro, M., Paños-Lozano, P. et al. Testicular neoplasms. Evaluation of the experience during 25 years in a military hospital. Clin Transl Oncol 8, 681–687 (2006). https://doi.org/10.1007/s12094-006-0039-3

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  • DOI: https://doi.org/10.1007/s12094-006-0039-3

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