References
Assassi S, Sharif R et al (2010) Predictors of interstitial lung disease in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort. Arthritis Res Ther 12(5):R166
Barnett AJ (1978) Scleroderma (progressive systemic sclerosis): progress and course based on a personal series of 118 cases. Med J Aust 2(4):129–134
Chifflot H, Fautrel B et al (2008) Incidence and prevalence of systemic sclerosis: a systematic literature review. Semin Arthritis Rheum 37:223–235
Choi HK, Hernan MA et al (2002) Methotrexate and mortality in patients with rheumatoid arthritis: a prospective study. Lancet 359(9313):1173–1177
Clements PJ (1995) Measuring disease activity and severity in scleroderma. Curr Opin Rheumatol 7(6):517–521
Cotter D, Zhang Y et al (2008) The effect of epoetin dose on hematocrit. Kidney Int 73(3):347–353
Goh NS, Desai SR et al (2008) Interstitial lung disease in systemic sclerosis: a simple staging system. Am J Respir Crit Care Med 177(11):1248–1254
Greidinger EL, Flaherty KT et al (1998). “African-American race and antibodies to topoisomerase I are associated with increased severity of scleroderma lung disease.” 114:801–807
Hernán M, Brumback B et al (2001) Marginal structural models to estimate the joint causal effect of nonrandomized treatments. J Am Stat Assoc 96(454):440–448
Hernan MA, Brumback BA et al (2002) Estimating the causal effect of zidovudine on CD4 count with a marginal structural model for repeated measures. Stat Med 21(12):1689–1709
Hoyles RK, Ellis RW et al (2006) A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma. Arthritis Rheum 54(12):3962–3970
Hudson M, Baron M et al (2011) Observational data to study medication outcomes in systemic sclerosis. J Rheumatol 38(3):575–577
MacKenzie EJ, Rivara FP et al (2006) A national evaluation of the effect of trauma-center care on mortality. N Engl J Med 354(4):366–378
Palella FJ Jr, Armon C et al (2009) The association of HIV susceptibility testing with survival among HIV-infected patients receiving antiretroviral therapy: a cohort study. Ann Intern Med 151(2):73–84
Plastiras SC, Karadimitrakis SP et al (2006) Scleroderma lung: initial forced vital capacity as predictor of pulmonary function decline. Arthritis Rheum 55(4):598–602
Rawlins M (2008) De testimonio: on the evidence for decisions about the use of therapeutic interventions. Lancet 372(9656):2152–2161
Roth MD, Tseng CH et al (2011) Predicting treatment outcomes and responder subsets in scleroderma-related interstitial lung disease. Arthritis Rheum 63(9):2797–2808
Rubin DB (1997) Estimating causal effects from large data sets using propensity scores. Ann Intern Med 127(8 Pt 2):757–763
Steele R, Hudson M et al (2011) A clinical decision rule to predict the presence of interstitial lung disease in systemic sclerosis. Arthritis Care Res (Hoboken) 64(4):519–524
Steen VD, Medsger TA (2007) Changes in causes of death in systemic sclerosis, 1972–2002. Ann Rheum Dis 66(7):940–944
Steen VD, Owens GR et al (1985) The effect of D-penicillamine on pulmonary findings in systemic sclerosis. Arthritis Rheum 28(8):882–888
Steen VD, Conte C et al (1994) Severe restrictive lung disease in systemic sclerosis. Arthritis Rheum 37(9):1283–1289
Sterne JA, Hernan MA et al (2005) Long-term effectiveness of potent antiretroviral therapy in preventing AIDS and death: a prospective cohort study. Lancet 366(9483):378–384
Tashkin DP, Elashoff R et al (2006) Cyclophosphamide versus placebo in scleroderma lung disease. N Engl J Med 354(25):2655–2666
White B (2003) Interstitial lung disease in scleroderma. Rheum Dis Clin N Am 29(2):371–390
Funding
This study was funded in part by the Canadian Institutes of Health Research, the Scleroderma Society of Canada and educational grants from Actelion Pharmaceuticals and Pfizer Inc. Dr. Hudson is supported by a Chercheur-clinicien boursier award from the Fonds de la Recherche en Santé du Québec. The funding sources had no role in the design of the study, analysis of the data, preparation of the manuscript and decision to submit for publication.
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Investigators of the Canadian Scleroderma Research Group: M. Baron, Montreal, Quebec; J. Pope, London, Ontario; J. Markland, Saskatoon, Saskatchewan; D. Robinson, Winnipeg, Manitoba; N. Jones, Edmonton, Alberta; N. Khalidi, Hamilton, Ontario; P. Docherty, Moncton, New Brunswick; E. Kaminska, Hamilton, Ontario; A. Masetto, Sherbrooke, Quebec; E. Sutton, Halifax, Nova Scotia; J-P. Mathieu, Montreal, Quebec; M. Hudson, Montreal, Quebec; S. Ligier, Montreal, Quebec; T. Grodzicky, Montreal, Quebec; Carter Thorne, Newmarket, Ontario; S. LeClercq, Calgary, Alberta; M. Fritzler, Mitogen Advanced Diagnostics Laboratory, Calgary, Alberta.
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Hudson, M., Steele, R., Canadian Scleroderma Research Group. et al. Immunosuppression for interstitial lung disease in systemic sclerosis – novel insights and opportunities for translational research. J. Cell Commun. Signal. 6, 187–190 (2012). https://doi.org/10.1007/s12079-012-0172-4
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DOI: https://doi.org/10.1007/s12079-012-0172-4