Abstract
Introduction
Thermal taster status (TTS) is determined when the tongue is cooled or warmed, whereby thermal tasters (TT) experience a taste sensation while thermal nontasters (TnT) do not. The literature suggests that TT experience greater responsiveness (higher intensity ratings) to orosensory stimuli; however, small sample sizes and differences in classification schemes between studies confound our understanding of TTS. In addition, up to 50% of individuals (nonclassifiables, NC) have been excluded from previous studies and have yet to be characterized.
Methods
Raw responses to the thermal-elicitation procedure were used to determine the TTS of the same participants using four published classification schemes, and concordance between the schemes was examined using Fleiss’ kappa. Using a large convenience sample (n = 708), we tested for differences in orosensory (ANOVA) and temperature (Mann-Whitney U) responsiveness between TT, TnT, and NC.
Results
TT are more responsive than TnT to both orosensations and temperature changes, regardless of the classification method used despite only moderate concordance between the schemes. Overall, the orosensory and temperature responsiveness of NC is intermediate to that of TT and TnT. However, the responses of NC are not homogeneous and subgroups are identified.
Conclusions
The trend of TT being more responsive to orosensory and temperature stimuli is confirmed. The responsiveness patterns of NC subgroups suggest they are misclassified TT and TnT, and can be included in future studies examining thermal tasting.
Implications
TTS is an important source of individual differences in orosensory responsiveness, and our findings inform best practices for thermal elicitation and classification.
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References
Bajec MR, Pickering GJ (2008) Thermal taste, PROP responsiveness, and perception of oral sensations. Physiol Behav 95:581–590
Bajec MR, Pickering GJ (2010) Association of thermal taste and PROP responsiveness with food liking, neophobia, body mass index and waist circumference. Food Qual Prefer 21:589–601
Bajec MR, Pickering GJ, DeCourville N (2012) Influence of stimulus temperature on orosensory perception and variation with taste phenotype. Chemosens Percept 5:243–265. https://doi.org/10.1007/s12078-012-9129-5
Bartoshuk LM, Duffy VB, Miller IJ (1994) PTC/PROP tasting: anatomy, psycophysics and sex effects. Physiol Behav 56:1165–1171
Bartoshuk LM, Cunningham KE, Dabrila GM et al (1999) From sweets to hot peppers: genetic variation in taste, oral pain, and oral touch. In: Bell GA, Watson AJ (eds) The chemical senses in science and industry. UNSW/Blackwell Science, Sydney
Bartoshuk LM, Duffy VB, Fast K et al (2002) Labeled scales (e.g., category, Likert, VAS) and invalid across-group comparisons: what we have learned from genetic variation in taste. Food Qual Prefer 14:125–138
Bartoshuk LM, Duffy VB, Green BG, Hoffman HJ, Ko CW, Lucchina LA, Marks LE, Snyder DJ, Weiffenbach JM (2004) Valid across-group comparisons with labeled scales: the gLMS versus magnitude matching. Physiol Behav 82:109–114
Bering AB, Pickering GJ, Liang P (2013) TAS2R38 single nucleotide polymorphisms are associated with PROP—but not thermal—tasting: a pilot study. Chemosens Percept 7:23–30. https://doi.org/10.1007/s12078-013-9160-1
Calo C, Padiglia A, Zonza A et al (2011) Polymorphisms in TAS2R38 and the taste bud trophic factor, gustin gene co-operate in modulating PROP taste phenotype. Physiol Behav 104:1065–1071
Cruickshanks KJ, Schubert CR, Snyder DJ, Bartoshuk LM, Huang GH, Klein BEK, Klein R, Nieto FJ, Pankow JS, Tweed TS, Krantz EM, Moy GS (2009) Mesuring taste impairment in epidemiologic studies: the beaver dam offspring study. Ann N Y Acad Sci 1170:543–552
Cruz A, Green BG (2000) Thermal stimulation of taste. Nature 403:889–892
Duffy VB, Davidson AC, Kidd JR, Kidd KK, Speed WC, Pakstis AJ, Reed DR, Snyder DJ, Bartoshuk LM (2004) Bitter receptor gene (TAS2R38), 6-n-propylthiouracil (PROP) bitterness and alcohol intake. Alcohol Clin Exp Res 28:1629–1637
Fischer ME, Cruickshanks KJ, Pankow JS et al (2014) The associations between 6-n-propylthiouracil (PROP) intensity and taste intensities differ by TAS2R38 haplotype. J Nutrigenet Nutrigenomics 7:143–152
Galindo-Cuspinera V, Waeber T, Antille N, Hartmann C, Stead N, Martin N (2009) Reliability of threshold and suprathrehold methods for taste phenotyping: characterization with PROP and sodium chloride. Chemosens Percept 2:214–228
Garcia-Bailo B, Toguri C, El-Sohemy A (2009) Genetic variation in taste and its influence on food selection. J Integr Biol 13:69–80
Green BG (2004) Temperature perception and nociception. Dev Neurobiol 61:13–29
Green BG, George P (2004) “Thermal taste” predicts higher responsiveness to chemical taste and flavour. Chem Senses 29:617–628
Green BG, Alvarez-Reeves M, George P, Akirav C (2005) Chemesthesis and taste: evidence of independent processing of sensation intensity. Physiol Behav 86:526–537
Hayes JE, Feeney EL, Allen AL (2013) Do polymorphisms in chemosensory genes matter for human ingestive behavior? Food Qual Prefer 30:202–216
Hort J, Ford RA, Eldeghaidy S, Francis ST (2016) Thermal taster status: evidence of cross-modal integration. Hum Brain Mapp 37:2263–2275
Kamerud JK, Delwiche JF (2007) Individual differences in perceived bitterness predict liking of sweetners. Chem Senses 32:803–810
Kim H-Y (2013) Statistical notes for clinical researchers: assessing normal distribution (2) using skewness and kurtosis. Restor Dent Endod 38:52–54. https://doi.org/10.5395/rde.2013.38.1.52
Kwiecien R, Kopp-Schneider A, Blettner M (2011) Concordance analysis. Dtsch Arztebl Int 108:515–521
Lakens D (2013) Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs. Front Psychol 4:1–12. https://doi.org/10.3389/fpsyg.2013.00863
Meiselman H (2015) A review of the current state of emotion research in product development. Food Res Int 76:192–199
Mitchell J, Castura JC, Thibodeau M, Pickering G (2018) Application of TCATA to examine variation in beer perception due to thermal taste status. Food Qual Prefer 73:135–142. https://doi.org/10.1016/j.foodqual.2018.11.016
Mojet J, Christ-Hazelhof E, Heidema J (2001) Taste perception with age: generic or specific losses in threshold sensitivity to the five basic tastes? Chem Senses 26:845–860
Pickering GJ, Hayes JE (2017) Influence of biological, experiential and psychological factors in wine preference segmentation. Aust J Grape Wine Res 23:154–161
Pickering GJ, Klodnicki CE (2016) Does liking and orosensation intensity elicited by sampled foods vary with thermal tasting? Chemosens Percept 9:47–55
Pickering GJ, Kvas R (2016) Thermal tasting and difference thresholds for prototypical tastes in wine. Chemosens Percept 9:37–46. https://doi.org/10.1007/s12078-016-9203-5
Pickering GJ, Bartolini J-A, Bajec MR (2010a) Perception of beer flavour associates with thermal taster status. J Inst Brew 116:239–244
Pickering GJ, Moyes A, Bajec MR, DeCourville N (2010b) Thermal taster status associates with oral sensations elicited by wine. Aust J Grape Wine Res 16:361–367
Pickering GJ, Lucas S, Gaudette N (2016) Variation in orosensation and liking of sampled foods with thermal tasting phenotype. Flavour 5
Prescott J, Ripandelli N, Wakeling I (2001) Binary taste mixture interactions in PROP non-tasters, medium-tasters and super-tasters. Chem Senses 26:993–1003
Skinner M, Eldeghaidy S, Ford R, Giesbrecht T, Thomas A, Francis S, Hort J (2018) Variation in thermally induced taste response across thermal tasters. Physiol Behav 188:67–78
Small-Kelly S, Pickering G (in revision) Variation in orosensory responsiveness to alcoholic beverages and their constituents - the role of the thermal taste phenotype. Chem Percept
Talavera K, Yasumatsu K, Voets T, Droogmans G, Shigemura N, Ninomiya Y, Margolskee RF, Nilius B (2005) Heat activation of TRPM5 underlies thermal taste sensitivity of sweet taste. Nature 438:1022–1025
Tepper BJ (2008) Nutritional implications of genetic taste variation: the role of PROP sensitivity and other taste phenotypes. Annu Rev Nutr 28:367–388
Yang Q, Hollowood T, Hort J (2014) Phenotypic variation in oronasal perception and the relative effects of PROP and thermal taster status. Food Qual Prefer 38:83–91
Yang Q, Dorado R, Chaya C, Hort J (2018) The impact of PROP and thermal taster status on the emotional response to beer. Food Qual Prefer 68:420–430
Acknowledgements
Alex Bartolini, Alison Moyes, Sarah Lucas, Atzin Gonzalez, Hannah Pickering, Stephanie Small-Kelly, Rachel Kvas, Lynda van Zuiden, and Catherine Klodnicki are sincerely thanked for assistance with collecting data. The contribution of the participants is gratefully acknowledged.
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This project was funded by a Natural Sciences and Engineering Research Council of Canada Discovery Grant to GP.
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The authors declare that they have no conflict of interest.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (Brock University Research Ethics Board, REB-05-258, 08-006, 08-065, 08-216, 10-193, 12-116, 12-181,14-119, 14-120, 15-018) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.
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Thibodeau, M., Saliba, A., Bajec, M. et al. Examination and Validation of Classification Schema for Determining Thermal Taste Status. Chem. Percept. 12, 69–89 (2019). https://doi.org/10.1007/s12078-019-09264-w
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DOI: https://doi.org/10.1007/s12078-019-09264-w