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Nasal Septum Deviation in Patients with Acute Invasive Fungal Rhinosinusitis in a Tertiary Care Hospital: A Cross-Sectional Study

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Abstract

This is a retrospective study exploring the demographics and the role of nasal septum deviation in acute invasive fungal rhinosinusitis (AIFS); and if this deviation contributes to the laterality predilection of this opportunistic infection. Fifty-six craniofacial CT scans were evaluated by two radiologists blinded to the clinical data and outcome for laterality of the disease; and nasal septal deviation (NSD). NSD was graded based on the measured septal angle of deviation into mild, moderate, and severe and furtherly classified into one of seven types based on Mladina’s classification. High prevalence of remarkable nasal septum deviation existed in our population with AIFS, with type 7 Mldina NSD represented the most prevalent in this population. We found no significant statistical relation between the side of deviation and the initial side of the fungal disease. We recommend screening for early manifestations of AIFS in similar debilitated patients; with high degrees of nasal septum deviation for considering it as an anatomical risk factor.

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Abbreviations

AIFS:

Acute invasive fungal rhino-orbital

NSD:

Nasal septal deviation

References

  1. Turner JH, Soudry E, Nayak JV, Hwang PH (2013) Survival outcomes in acute invasive fungal sinusitis: a systematic review and quantitative synthesis of published evidence. Laryngoscope 123:1112–1118

    Article  PubMed  Google Scholar 

  2. Fouad YA, Abdelaziz TT, Askour MA, Saleh MI, Mahmoud MS, Ashour DM, Ashour MM (2021) Spike in rhino-orbital-cerebral mucormycosis cases presenting to a tertiary care center during the COVID-19 pandemic. Front Med (Lausanne) 28(8):645270

    Article  Google Scholar 

  3. Kurokawa M, Kurokawa R, Baba A, Kim J, Tournade C, Mchugh J, Trobe J, Srinivasan A, Bapuraj J, Moritani T (2022) Deadly fungi: invasive fungal rhinosinusitis in the head and neck. Radiographics 42:2075–2094

    Article  PubMed  Google Scholar 

  4. Selarka L, Sharma S, Saini D et al (2021) Mucormycosis and COVID-19: an epidemic within a pandemic in India. Mycoses 64(10):1253–1260

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Hoenigl M, Seidel D, Carvalho A, Rudramurthy SM, Arastehfar A, Gangneux JP, Nasir N, Bonifaz A, Araiza J, Klimko N, Serris A, Lagrou K, Meis JF, Cornely OA, Perfect JR, White PL, Chakrabarti A (2022) The emergence of COVID-19 associated mucormycosis: a review of cases from 18 countries. Lancet Microbe 3:e543–e552

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh T, Kontoyiannis D (2012) Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis 54:S23–S34

    Article  PubMed  Google Scholar 

  7. Most SP, Rudy SF (2017) Septoplasty: basic and advanced techniques. Facial Plast Surg Clin North Am 25(2):161–169. https://doi.org/10.1016/j.fsc.2016.12.002

    Article  PubMed  Google Scholar 

  8. Azila A, Irfan M, Rohaizan Y, Shamim A (2011) The prevalence of anatomical variations in osteomeatal unit in patients with chronic rhinosinusitis. Med J Malaysia 66:191–194

    CAS  PubMed  Google Scholar 

  9. Sharma Y, Mishra G, Pancholi K et al (2021) Does degree of nasal septal deviation measured with CT PNS have a role in management of deviated nasal septum? Indian J Otolaryngol Head Neck Surg. https://doi.org/10.1007/s12070-021-02831-2

    Article  PubMed  PubMed Central  Google Scholar 

  10. Polat C, Dostbil Z (2010) Evaluation of the nasal mucociliary transport rate by rhinoscintigraphy before and after surgery in patients with deviated nasal septum. Eur Arch Otorhinolaryngol 267:529–535

    Article  PubMed  Google Scholar 

  11. Aribandi M, McCoy VA, Bazan C (2007) Imaging features of invasive and non invasive fungal sinusitis: a review. Radiogr Rev Publ Radiol Soc N Am 27:1283–1296

    Google Scholar 

  12. Middlebrooks EH et al (2015) Acute invasive fungal rhinosinusitis: a comprehensive update of CT findings and design of an effective diagnostic imaging model. AJNR Am J Neuroradiol 36:1529–1535

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Fernandez I, Stanzani M, Tolomelli G, Pasquini E, Vianelli N, Baccarani M, Sciarretta V (2011) Sinonasal risk factors for the development of invasive fungal sinusitis in hematological patients: are they important? Allergy Rhinol 2:6–11

    Article  Google Scholar 

  14. Oshima H, Nomura K, Sugawara M, Arakawa K, Oshima T, Katori Y (2014) Septal deviation is associated with maxillary sinus fungus ball in male patients. Tohoku J Exp Med 232:201–206

    Article  PubMed  Google Scholar 

  15. Tsai TL, Lan MY, Ho CY (2012) There is no structural relationship between nasal septal deviation, concha bullosa, and paranasal sinus fungus balls. Sci World J 1:1–4

    Google Scholar 

  16. Epstein V, Kern R (2008) Invasive fungal sinusitis and complications of rhinosinusitis. Otolaryngol Clin North Am 41:497–524

    Article  PubMed  Google Scholar 

  17. Mladina R, Čujić E, Šubarić M, Vuković K (2008) Nasal septal deformities in ear, nose, and throat patients: an international study. Am J Otolaryngol 29:75–82

    Article  PubMed  Google Scholar 

  18. Mladina R, Skitarelić N, Poje G, Šubarić M (2015) Clinical implications of nasal septal deformities. Balkan Med J 32(2):137–146. https://doi.org/10.5152/balkanmedj.2015.159957

    Article  PubMed  PubMed Central  Google Scholar 

  19. Elahi MM, Frenkiel S, Fageeh N (1997) Paraseptal structural changes and chronic sinus disease in relation to the deviated septum. J Otolaryngol 26(3):236–240

    CAS  PubMed  Google Scholar 

  20. Khademi B, Dehghan A, Zia Z, Dehghan Y (2022) Imaging spectrum of Coronavirus disease- 2019 associated rhino-orbital-cerebral mucormycosis; from sinonasal inflammation to intracranial involvement. Acad Radiol. https://doi.org/10.1016/j.acra.2022.12.011

    Article  PubMed  PubMed Central  Google Scholar 

  21. Mohebbi A, Ahmadi A, Etemadi M, Safdarian M, Ghourchian S (2012) An epidemiologic study of factors associated with nasal septum deviation by computed tomography scan: a cross sectional study. BMC Ear Nose Throat Disord 12:15

    Article  PubMed  PubMed Central  Google Scholar 

  22. Slonimsky G, McGinn J, Goyal N, Crist H, Hennessy M, Gagnon E, Slonimsky E (2020) A model for classification of invasive fungal rhinosinusitis by computed tomography. Sci Rep 10:12591

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Manar M. Ashour.

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Ashour, M.M., Abdelaziz, T.T., Mahmoud, M.S. et al. Nasal Septum Deviation in Patients with Acute Invasive Fungal Rhinosinusitis in a Tertiary Care Hospital: A Cross-Sectional Study. Indian J Otolaryngol Head Neck Surg (2024). https://doi.org/10.1007/s12070-023-04438-1

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